<p>Control or MerTK<sup>−/−</sup> mice received sponges for 14 days. (A) Flow cytometry analysis was used to determine the proportion of F4/80<sup>+</sup> macrophages and Ly6G<sup>+</sup> neutrophils in the day 14 wounds of control and MerTK<sup>−/−</sup> mice. (B) The F4/80<sup>+</sup> macrophage population was assessed for the frequency of Ly6C<sup>hi</sup> and Ly6C<sup>low</sup> subsets. (C) The expression of activated caspase-3/7 was determined by FACS in control (blue histogram) and MerTK<sup>−/−</sup> (red histogram) mice at 14 days after wounding. The negative control is shown as a grey histogram. As an indication of neutrophil phagocytosis by wound monocytes/macrophages (Mo/Mφ), the frequency (D) and number (E) of Ly6C<sup>hi</sup> ...
<p>Wounds were harvested on day 5 post-injury and cryosections from the center of each wound were st...
<p>(A) Differential counts for macrophages were assessed ex vivo using cytospin smears of BAL sample...
<p><b><i>A</i>,</b> Schematic of the experimental protocol for periodic macrophage and DC ablation i...
<p>C57BL/6J mice were wounded for 1, 3, 7 or 14 days. Wound cells were isolated and examined by flow...
<div><p>The origin of wound repair macrophages is incompletely defined and was examined here in ster...
<p>Sponges were implanted into CD45.1 congenic mice. At 1 day post-wounding, sponges were transferre...
<p>Gated F4/80<sup>+</sup>Ly6C<sup>hi</sup> blood monocytes from naïve and day 1-wounded C57BL/6J mi...
<p>C57BL/6J mice were wounded for 1 or 14 days, and the surface expression of MHC class II, CD11c an...
<p>(A) Blood cells were isolated from naïve, day 1 and day 7-wounded C57BL/6J mice. Gated F4/80<sup>...
<p>Three mm full thickness excisional wounds were made on dorsal skin of IL-4 Tg and WT mice. At var...
Mice were wounded by PVA sponge implantation and uninfected or infected with IAV 24 hours later. Con...
<p>Mice were wounded for 14 days. Cytokine and growth factor concentrations were measured in wound f...
<p>F4/80<sup>+</sup>Ly6C<sup>hi</sup> monocytes/macrophages were sorted from day 1 wound cells. F4/8...
<p>(<b>a</b>) Representative TPLSM picture of the wound deep skin layer from MacBlue×CX3CR1<sup>gfp/...
<p>At day 7 post-surgery, the wound skin tissues were analyzed immunochemically and by qRT-PCR. Show...
<p>Wounds were harvested on day 5 post-injury and cryosections from the center of each wound were st...
<p>(A) Differential counts for macrophages were assessed ex vivo using cytospin smears of BAL sample...
<p><b><i>A</i>,</b> Schematic of the experimental protocol for periodic macrophage and DC ablation i...
<p>C57BL/6J mice were wounded for 1, 3, 7 or 14 days. Wound cells were isolated and examined by flow...
<div><p>The origin of wound repair macrophages is incompletely defined and was examined here in ster...
<p>Sponges were implanted into CD45.1 congenic mice. At 1 day post-wounding, sponges were transferre...
<p>Gated F4/80<sup>+</sup>Ly6C<sup>hi</sup> blood monocytes from naïve and day 1-wounded C57BL/6J mi...
<p>C57BL/6J mice were wounded for 1 or 14 days, and the surface expression of MHC class II, CD11c an...
<p>(A) Blood cells were isolated from naïve, day 1 and day 7-wounded C57BL/6J mice. Gated F4/80<sup>...
<p>Three mm full thickness excisional wounds were made on dorsal skin of IL-4 Tg and WT mice. At var...
Mice were wounded by PVA sponge implantation and uninfected or infected with IAV 24 hours later. Con...
<p>Mice were wounded for 14 days. Cytokine and growth factor concentrations were measured in wound f...
<p>F4/80<sup>+</sup>Ly6C<sup>hi</sup> monocytes/macrophages were sorted from day 1 wound cells. F4/8...
<p>(<b>a</b>) Representative TPLSM picture of the wound deep skin layer from MacBlue×CX3CR1<sup>gfp/...
<p>At day 7 post-surgery, the wound skin tissues were analyzed immunochemically and by qRT-PCR. Show...
<p>Wounds were harvested on day 5 post-injury and cryosections from the center of each wound were st...
<p>(A) Differential counts for macrophages were assessed ex vivo using cytospin smears of BAL sample...
<p><b><i>A</i>,</b> Schematic of the experimental protocol for periodic macrophage and DC ablation i...