Cytokine production by wound monocyte/macrophage subsets.

<p>F4/80⁺Ly6C^hi monocytes/macrophages were sorted from day 1 wound cells. F4/80⁺Ly6C^hi and Ly6C^low monocytes/macrophages were sorted from day 14 wound cells. Sorted populations were cultured as described in Materials & Methods and supernatants were tested by ELISA for (A) IL-1β, (B) TNF-α, (C) TGF-β and (D) VEGF production. Data shown are the mean ± SD; n = 3 mice per experiment; data represent 2–3 independent experiments. # = below the level of detection.