Immunogenicity of r<i>Tm</i>-WAP-F8+<i>Na</i>-GST-1 and r<i>Tm</i>-WAP49 proteins in a murine model.
- Neima Briggs (3213657)
- Junfei Wei (348662)
- Leroy Versteeg (4248760)
- Bin Zhan (11041)
- Brian Keegan (121761)
- Ashish Damania (3279987)
- Jeroen Pollet (2234860)
- Kelly S. Hayes (734419)
- Coreen Beaumier (5693285)
- Christopher A. Seid (3825676)
- Jamie Leong (5693288)
- Richard K. Grencis (102308)
- Maria Elena Bottazzi (11043)
- K. Jagannadha Sastry (221197)
- Peter J. Hotez (145727)
Publication date
September 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
Humoral immune response was measured by end-point serum titer for antigen-specific (A) IgG1and (B) IgG2a by ELISA to calculate the (C) IgG1 to IgG2a ratio for the mice in each group. Mice in groups injected Montanide ISA 720 adjuvant were used as negative controls for each coating antigen. Values from duplicate wells for each treatment/stimulation were averaged for individual cytokines for the 15 mice in each group to calculate statistical significance. Statistical significance: *p<0.05, **p<0.01 ***p<0.001, ****p<0.0001.</p
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