<p>The colored boxes in the loci pane represent the DNA methylation measurements as distributed over the various functional differentially methylated regions, also defined by unique coloring (<i>H19</i> DMR, <i>IGF2</i> DMR2, DMR1, DMR0 and the <i>INS</i> promoter). The number of CpG sites measured per locus is given above the locus names. The gene structure, as defined by Refseq, is given together with the CpG islands (“CGI”, bright green). The yellow bar presents the chromosome, with the various measured SNPs marked by bars. In the HaploView pane the D′ between SNPs is given in the color scale, while the R-squared is given in numeric values in the boxes.</p
<p>Each genomic region where DNA methylation was measured is highlighted in yellow and numbered 1–3....
<p>The red rectangle represents the portion of this gene that was amplified by the nested primers. B...
<p>The SNP distribution and haplotype block structure across the CAST gene are shown, respectively. ...
<p>The colored bars present DNA methylation measurements of the various loci and their grouping in t...
<p>Schematic of CpG site distributions in the putative DMRs of imprinted gene <i>IGF2R</i>; Vertical...
<p>Graphical representation of chromosome wide distribution of methylation peaks of chromosome 1, 2 ...
<p>This demonstrates the first exons of either the <i>VHL</i> gene (A) or the <i>SFRP1</i> gene (B) ...
<p>A. Schematic representation of the 11p15 locus. The 11p15 locus is represented with the 2 differe...
<p>(A) and (D): The genomic profile of genes displayed in UCSC (hg19), the genomic locus of target r...
<p>Schematic of CpG site distributions in the putative DMRs of <i>H19</i>; Vertical red lines repres...
<p>Illustrations showing genomic context and individual CpG methylation levels at three separate MPR...
<p>A) Pedigree showing the relationship of family members. B) Heat map showing the methylation level...
<p>The bars sum up the DNA methylation status of all CpG dyads. The map next to the bar represents t...
<p>A. Schematic representation of a segment encompassing 21 CpG dinucleotides (CG1→CG21) within the ...
<p>CpGs within DMRs are annotated between colored vertical lines. (A) <i>RUNX1</i>, overlapping (4 o...
<p>Each genomic region where DNA methylation was measured is highlighted in yellow and numbered 1–3....
<p>The red rectangle represents the portion of this gene that was amplified by the nested primers. B...
<p>The SNP distribution and haplotype block structure across the CAST gene are shown, respectively. ...
<p>The colored bars present DNA methylation measurements of the various loci and their grouping in t...
<p>Schematic of CpG site distributions in the putative DMRs of imprinted gene <i>IGF2R</i>; Vertical...
<p>Graphical representation of chromosome wide distribution of methylation peaks of chromosome 1, 2 ...
<p>This demonstrates the first exons of either the <i>VHL</i> gene (A) or the <i>SFRP1</i> gene (B) ...
<p>A. Schematic representation of the 11p15 locus. The 11p15 locus is represented with the 2 differe...
<p>(A) and (D): The genomic profile of genes displayed in UCSC (hg19), the genomic locus of target r...
<p>Schematic of CpG site distributions in the putative DMRs of <i>H19</i>; Vertical red lines repres...
<p>Illustrations showing genomic context and individual CpG methylation levels at three separate MPR...
<p>A) Pedigree showing the relationship of family members. B) Heat map showing the methylation level...
<p>The bars sum up the DNA methylation status of all CpG dyads. The map next to the bar represents t...
<p>A. Schematic representation of a segment encompassing 21 CpG dinucleotides (CG1→CG21) within the ...
<p>CpGs within DMRs are annotated between colored vertical lines. (A) <i>RUNX1</i>, overlapping (4 o...
<p>Each genomic region where DNA methylation was measured is highlighted in yellow and numbered 1–3....
<p>The red rectangle represents the portion of this gene that was amplified by the nested primers. B...
<p>The SNP distribution and haplotype block structure across the CAST gene are shown, respectively. ...