Graphical representation of the SNP locations and LD structure of the CAST gene.

<p>The SNP distribution and haplotype block structure across the CAST gene are shown, respectively. Each figure was composed of chromosome scale (the top line with even division), the transcription string (the thick bars represent exon (yellow) or UTR (blue), the thin lines represent intron), SNP scale (the hollow bar with scales representing SNP location), and graphic of LD (black-and-white, Fig. 1A) or block definition (red, Fig. 1B). The lighter and darker shades in Fig. 1A represent lower and higher values of the LD (D′) among all possible SNP pairs respectively. The numbers in squares are D′ values multiplied by 100. Haplotype blocks were defined according to the criteria by Gabriel et al. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0070935#pone.0070935-Gabriel1" target="_blank">[34]</a>. In Fig. 1B, lower values of LD (r²) among all possible pairs of SNPs are represented by lighter shades of color and scarlet represents higher r² values. The numbers in squares are r² values multiplied by 100.