SNPs in the region of MMP-1 gene located in chromosome 11q22.

<p><b>A</b>, MMP-1 gene structure. Filled boxes represent the exons (5′→3′). Arrows show the locations of SNPs. <b>B</b>: Mapping of the block structure of the seven SNPs generated by Haploview. The value within each square in the triangle plot represents the pairwise correlation between SNPs (measured as D′) defined by the upper left and the upper right sides of the Squares. The Squares without a number correspond to D′=1. Shading represents the magnitude and significance of pairwise LD, with a red-to-white gradient reflecting higher to lower LD values. The frequency of each common haplotype within a block is to the right of the haplotype.