<p>Results are presented as absorbance (arbitrary value) mean ± SE, n = 4. IR, insulin receptor; IGF-1, insulin-like growth factor 1.</p
<p>The calculated complex concentrations are normalized to total receptor concentration (<i>i.e. c<s...
Objective: To investigate whether human insulin (HI) and insulin analogues differ in their ability t...
<p>For all studies, groups are control (ctrl), diabetic (Diabetic), Diabetic +IGFBP-3 NB (Diab +BP3)...
<p>Results are presented as mean ± SE, n = 8. IR, insulin receptor; IGF-1, insulin-like growth facto...
<p>Receptor binding affinities for the solubilised IR-A (light teal), IR-B (dark teal) and IGF-IR (g...
<p>Affinities were determined by insulin competition binding in a scintillation proximity assay; dat...
<p>All assays were performed in at least three independent experiments. Data are means ± SD and pres...
The insulin/insulin-like growth factor signaling axis is a complex system that is involved in the re...
<p>Binding of the insulin analogs to the human IR-A (<b>A</b>) or IR-B (<b>B</b>) was analyzed in a ...
<p><b>A:</b> Comparison of full-length MGF (red points and line) and insulin (green points and line)...
<p><b>A:</b> Representative insulin receptor binding curves for HI(black), B25C-NEM1 (dark gray) B25...
<p>IC50 values were determined in scintillation proximity assays for displacement of <sup>125</sup>I...
with regard to their insulin receptor (IR) and IGF-1 receptor (IGF1R) binding and signaling propert...
The metabolic activity of insulin has been studied extensively in vitro and in vivo, based on the in...
Modern lifestyle with its lack of exercise and healthy diet often leads to obesity which is accompan...
<p>The calculated complex concentrations are normalized to total receptor concentration (<i>i.e. c<s...
Objective: To investigate whether human insulin (HI) and insulin analogues differ in their ability t...
<p>For all studies, groups are control (ctrl), diabetic (Diabetic), Diabetic +IGFBP-3 NB (Diab +BP3)...
<p>Results are presented as mean ± SE, n = 8. IR, insulin receptor; IGF-1, insulin-like growth facto...
<p>Receptor binding affinities for the solubilised IR-A (light teal), IR-B (dark teal) and IGF-IR (g...
<p>Affinities were determined by insulin competition binding in a scintillation proximity assay; dat...
<p>All assays were performed in at least three independent experiments. Data are means ± SD and pres...
The insulin/insulin-like growth factor signaling axis is a complex system that is involved in the re...
<p>Binding of the insulin analogs to the human IR-A (<b>A</b>) or IR-B (<b>B</b>) was analyzed in a ...
<p><b>A:</b> Comparison of full-length MGF (red points and line) and insulin (green points and line)...
<p><b>A:</b> Representative insulin receptor binding curves for HI(black), B25C-NEM1 (dark gray) B25...
<p>IC50 values were determined in scintillation proximity assays for displacement of <sup>125</sup>I...
with regard to their insulin receptor (IR) and IGF-1 receptor (IGF1R) binding and signaling propert...
The metabolic activity of insulin has been studied extensively in vitro and in vivo, based on the in...
Modern lifestyle with its lack of exercise and healthy diet often leads to obesity which is accompan...
<p>The calculated complex concentrations are normalized to total receptor concentration (<i>i.e. c<s...
Objective: To investigate whether human insulin (HI) and insulin analogues differ in their ability t...
<p>For all studies, groups are control (ctrl), diabetic (Diabetic), Diabetic +IGFBP-3 NB (Diab +BP3)...
DOI
Add to ORKG