Relative binding affinities for Hybrid-A (IR-A/IGF-1R) and Hybrid-B (IR-B/IGF-1R).

<p>IC50 values were determined in scintillation proximity assays for displacement of ¹²⁵I-IGF-1 from receptors with human insulin, IGF-1, insulin X10, insulin detemir or insulin glargine. Relative binding compared to human insulin binding is given in percent. Data represent mean (±SD) from three independent experiments.</p><p>IGF-1, insulin-like growth factor 1.