B cell depletion in CD22-cal treated mice.

<p>Mice were treated with CD22-cal at days −6 and −1 and were immunized with 400 µg G6PI in complete Freund's adjuvant. Control mice were immunized but otherwise left untreated. Lymph nodes (LN), spleens and bone marrow were isolated, counted and analyzed for the percentage of CD19⁺ B and CD3⁺ T lymphocytes. Shown are the total number cells harvested (left) or the total number of B- (middle) or T-lymphocytes (right) in the various organs. Data are representative for at least three mice per time point.