Decrease in both B cells and T cells in B6.<i>Baff^−/−</i> mice and increase in both B cells and T cells in B6.BTg mice.

<p>Panel A: Spleen (top) or LN (bottom) cells from representative B6 WT (WT), B6.<i>Baff^−/−</i> (KO), and B6.BTg (Tg) mice were stained for surface CD3 and surface CD19 expression. The values adjacent to the boxes in each tracing indicate the percentages of CD3⁺ or CD19⁺ cells in that sample. Panel B: Results (mean ± SEM) are presented for total spleen CD3⁺, CD4⁺, CD8⁺, and CD19⁺ cells for the 6 mice in each cohort. Panel C: Results (mean ± SEM) are presented for LN CD4⁺CD69⁺, CD4⁺CD44^hi, and CD4⁺CD62L^lo cells for the 6 mice in each cohort. *, p≤0.05; **, p≤0.01; ***, p≤0.001 in comparison to WT values.