GAT1 KO mice show exaggerated locomotor responses to novelty but impaired object recognition memory.

<p><b><i>A</i></b>, GAT1 KO mice spent more time in the proximity of the novel objects A and B as compared to WT in 5-min tests. n = 12–13 for each group, ** <i>p</i><0.01, ^##<i>p</i><0.01 vs WT, ANOVA. <b><i>B</i></b>, After 1 day, object A was changed to a novel object C. WT mice spent more time in the proximity of the object C than that of object B, indicating a object recognition memory. This memory was impaired in GAT1 KO mice. n = 12–13 for each group, * <i>p</i><0.05 vs object C, ANOVA.