RAGEΔICD affects S100B induced cellular migration.

<p><b>A–B.</b> C6 glioma cells expressing RAGE, RAGEΔICD, or empty vector (mock) were assessed for S100B induced migration using chemotaxis assays. Cells were seeded into the upper chamber of a Boyden transwell filters and allowed to migrate toward 5 ug/ml S100B stimulant for 24 hours. <b>A</b>. Representative images are shown. <b>B.</b> quantitation of relative cell migration normalized to mock transfected cells. Data are means ± SEM from three independent experiments, where *, significant differences (P = 0.03) between groups; and #, p = 0.006.