Validation of Microarray Data.

<p>A custom PCR array was used to validate the fold changes found in the original microarray experiment. At the 4 week time point, 6 of the 8 genes investigated reached statistical significance, indicating the increased severity of the phenotype at the earlier time point. Ddr1 was the most highly up-regulated gene found with the most statistically significant p-value, thus prompting further investigation of the possible relationship between Jag1 and Ddr1. (* = p≤0.05; ** = p≤0.01).