Effects of T0901317 on insulin function.

<p>A–F, Body weight (A, <i>n</i> = 14–16 mice per group), glucose levels and glucose level area under the curve (AUC) during an intraperitoneal glucose test (IPGTT, 1.5 g glucose per kg body weight) (B), insulin levels and insulin level area under the curve (AUC) during IPGTT (C, <i>n</i> = 7–8 mice per group), glucose levels and glucose level area under the curve (AUC) during an insulin tolerance test (ITT, 0.5 IU insulin per kg body weight, <i>n</i> = 7–8 mice per group) (D), free fatty acid levels (E) and triglyceride levels in serum after an overnight fast (<i>n</i> = 7–8 mice per group). All values are presented as mean ± SEM, *<i>P</i><0.05 and **<i>P</i><0.01 vs. control mice treated with DMSO.