Effects of OA on glucose tolerance and blood insulin.

<p>Studies were performed in mice two weeks after the removal of OA. ipGTT was performed with an injection of glucose (1 g/kg, <i>ip</i>) after 5–7 hours of fasting. Blood glucose was monitored at 0, 15, 30, and 60 min following the glucose injection (<i>A</i>). ipGTT results were quantified by calculating the area under the blood glucose curve (AUC) and the incremental AUC (iAUC) (<i>B</i>). Insulin levels throughout the ipGTT (<i>C</i>). The average value of blood insulin levels from 5 to 60 mins during the ipGTT (<i>D</i>). CH, normal chow fed mice; T2D-Veh, HF-fed mice with STZ injections; T2D-OA, HF-fed mice with STZ injections and OA treatment. ** p<0.01 vs. CH; †† p<0.01 vs. T2D-Veh, n = 5–8 per group.