Cellular responses in vaccinated hamsters. LTT response

<p>(mean O.D value) to combinations and ConA in normal, infected control, BCG control, rLdHSP70 control groups as well as in group 5–11 vaccinated hamsters <b>(A)</b> on days 45, and <b>(B)</b> on day 90 p.c. Significance values indicate the difference between the vaccinated groups and infected group. <b>NO production</b> (µM) to LPS and combinations of rLdHSP70 in the naive macrophages co-incubated with supernatants of mononuclear cells isolated from respective group of vaccinated hamsters in comparison to the unimmunized infected controls, BCG immunized controls, rLdHSP70 control and uninfected normal hamsters <b>(C)</b> on day 45, and <b>(D)</b> on day 90 p.c. <b>DTH response</b> (mm) to soluble <i>L. donovani</i> (SLD) as footpad swelling on day 90 p.c <b>(E)</b>. Significance values indicate the difference between the vaccinated groups and infected group (*, p<0.05; **, p<0.01; and ***, p<0.001).