Antibody response in vaccinated hamsters.

<p>(A) IgG and its isotypes (B) IgG1and (C) IgG2 in rLdEno-vaccinated hamsters in comparison to the unimmunized infected hamsters on days 45, 60, and 90 p.c. Serum samples were collected from different groups of hamsters at designated time points and assayed for rLdEno/rLdAld- specific IgG, IgG1, and IgG2 levels by ELISA. Data are presented as the absorbance at 492 nm and are means ± SE for 3–4 hamsters per group in triplicate wells. Data are representative of two independent experiments with similar results. Significance values indicate the difference between the vaccinated and infected group (*, <i>p</i><0.05; **, <i>p</i><0.01; and ***, <i>p</i><0.001).