<p>A, DTH response before and after 2 and 3 months post infection. B, serum IgG, IgG1 and IgG2 at 10 days after final vaccination. C, IgG, IgG1 and IgG2 response after 3 months post infection. Data are presented as the mean absorbance at 450 nm ± S.E., ***, <i>p</i><0.0001, ns = not significant. Asterisks over each bar indicate significant differences in comparison to adjuvant controls. Asterisks over line indicate significant differences between groups. *, <i>p</i><0.05; **, <i>p</i><0.01. The results are mean ± S.E. of five individual hamsters per group, representative of two independent experiments with similar results.</p
<p>Groups of 4 animals were sacrificed on the specified days post-infection for analysis of A) serum...
<p>Hamsters (n = 6–10) were bled 2 weeks after immunization and sera were tested by ELISA to determi...
<p>Significance values indicate the difference between the vaccinated group and infected group (*, p...
<p>(A) IgG and its isotypes (B) IgG1and (C) IgG2 in rLdEno-vaccinated hamsters in comparison to the ...
<p>(mean O.D value) to combinations and ConA in normal, infected control, BCG control, rLdHSP70 cont...
<p>Recombinant rOmpL37 expressed by <i>E</i>. <i>coli</i> was used as the antigen in ELISA. Mean val...
<p>Fold change in mRNA expression profiles of A, IFN-γ; B, IL-12; C, TNF-α; D, IL-4; E, TGF-β; F, IL...
<p>Hamster immunoglobulin responses to heat-killed leptospires were measured by ELISA. Mean and stan...
<p>Significance values indicate the difference between the vaccinated group and infected group (*, p...
<p>Host #: R = rabbit; GP = guinea pig. Peak Time: Hamsters were perfused at the time of expected pe...
<p>Data are presented as means ± SE and are representative of two independent experiments with simil...
<p>A) Survival curve of hamsters challenged with 4,000 PFU i.n. of ANDV on day 0, then passively tra...
<p>Th2 cytokines mRNA expression profile analysis of normal and immunized hamsters on days 45 p.c.an...
<p>Hamsters (n = 15) were immunized with HIS or LiP0 antigens using the homologous (DNA only) or het...
<p>(A) DTH response (mm); (B&C) LTT response (mean O.D value) to SLD and ConA in normal, infected co...
<p>Groups of 4 animals were sacrificed on the specified days post-infection for analysis of A) serum...
<p>Hamsters (n = 6–10) were bled 2 weeks after immunization and sera were tested by ELISA to determi...
<p>Significance values indicate the difference between the vaccinated group and infected group (*, p...
<p>(A) IgG and its isotypes (B) IgG1and (C) IgG2 in rLdEno-vaccinated hamsters in comparison to the ...
<p>(mean O.D value) to combinations and ConA in normal, infected control, BCG control, rLdHSP70 cont...
<p>Recombinant rOmpL37 expressed by <i>E</i>. <i>coli</i> was used as the antigen in ELISA. Mean val...
<p>Fold change in mRNA expression profiles of A, IFN-γ; B, IL-12; C, TNF-α; D, IL-4; E, TGF-β; F, IL...
<p>Hamster immunoglobulin responses to heat-killed leptospires were measured by ELISA. Mean and stan...
<p>Significance values indicate the difference between the vaccinated group and infected group (*, p...
<p>Host #: R = rabbit; GP = guinea pig. Peak Time: Hamsters were perfused at the time of expected pe...
<p>Data are presented as means ± SE and are representative of two independent experiments with simil...
<p>A) Survival curve of hamsters challenged with 4,000 PFU i.n. of ANDV on day 0, then passively tra...
<p>Th2 cytokines mRNA expression profile analysis of normal and immunized hamsters on days 45 p.c.an...
<p>Hamsters (n = 15) were immunized with HIS or LiP0 antigens using the homologous (DNA only) or het...
<p>(A) DTH response (mm); (B&C) LTT response (mean O.D value) to SLD and ConA in normal, infected co...
<p>Groups of 4 animals were sacrificed on the specified days post-infection for analysis of A) serum...
<p>Hamsters (n = 6–10) were bled 2 weeks after immunization and sera were tested by ELISA to determi...
<p>Significance values indicate the difference between the vaccinated group and infected group (*, p...