<p>Hepatic Cyp7a1 mRNA expression after a control (A) or 0.5%-CA (wt/wt) chow diet (B) for three weeks. Cyp7a1 mRNA levels were normalized to a housekeeping gene (β-actin) in <i>Cftr</i> knockout mice (<i>Cftr</i><sup><i>-/-</i></sup>) and control littermates (<i>Cftr</i><sup><i>+/+</i></sup>). Data are presented as means ± SEM of N = 5–7 mice per group. *P-value<0.05.</p
Histone deacetylases (HDACs) are involved in the regulation of cholesterol 7alpha-hydroxylase gene (...
<p>(A) mRNA expression levels of <i>Cyp7a1</i>, <i>Cyp8b1, Cyp27a1, Shp</i>, <i>Fxr</i>, <i>Pgc-1α</...
<p>The C16:1/C16:0, C18:1/C18:0 (A) and C18:0/C16:0 (B) ratios were calculated, based on data obtain...
<p>Body weight (A, B), absolute liver weight (C,D) and relative liver weight reported as a percentag...
<p>Histological evaluation of liver parenchymal inflammation (A), parenchymal Ki67 activity (B), por...
<p>Liver histology (magnification 40x) of <i>Cftr</i> knockout mice (<i>Cftr</i><sup><i>-/-</i></sup...
<p>The mRNAs of key factors that regulate basal Cyp7a1 transcription (HNF4α, LRH-1, and PGC-1α) and ...
<p>Livers from wt and <i>Slc10a2</i>−/− mice fed regular chow or a SR diet were analysed for A), mRN...
<p><b>A</b> One-way hierarchical cluster map of cholesterol biosynthesis genes that changed signific...
<p>C57BL/6J mice were fed a standard chow (NC), a CL diet (CL), or a CL diet containing 0.003% β-cry...
<p>Control wild-type and <i>db/db</i> (left panels) or <i>ob/ob</i> (right panels) male mice on the ...
<p>Gene expression of A) <i>Acaca</i>, B) <i>Adh1</i>, C) <i>Cpt1a</i>, D) <i>Cyp2e1</i>, E) <i>Dgat...
<p>Total RNA was extracted from liver tissues of male wild type or <i>Tet-mev-1</i> mice (<i>+ROS</i...
<p><b>activates enzymes in BA synthesis.</b> (A) mRNA levels of cholesterol 7α-hydroxylase (Cyp7a1) ...
ICR mice were fed with either a CFD or control diet for 25 weeks. Mice were weighed every week. (A) ...
Histone deacetylases (HDACs) are involved in the regulation of cholesterol 7alpha-hydroxylase gene (...
<p>(A) mRNA expression levels of <i>Cyp7a1</i>, <i>Cyp8b1, Cyp27a1, Shp</i>, <i>Fxr</i>, <i>Pgc-1α</...
<p>The C16:1/C16:0, C18:1/C18:0 (A) and C18:0/C16:0 (B) ratios were calculated, based on data obtain...
<p>Body weight (A, B), absolute liver weight (C,D) and relative liver weight reported as a percentag...
<p>Histological evaluation of liver parenchymal inflammation (A), parenchymal Ki67 activity (B), por...
<p>Liver histology (magnification 40x) of <i>Cftr</i> knockout mice (<i>Cftr</i><sup><i>-/-</i></sup...
<p>The mRNAs of key factors that regulate basal Cyp7a1 transcription (HNF4α, LRH-1, and PGC-1α) and ...
<p>Livers from wt and <i>Slc10a2</i>−/− mice fed regular chow or a SR diet were analysed for A), mRN...
<p><b>A</b> One-way hierarchical cluster map of cholesterol biosynthesis genes that changed signific...
<p>C57BL/6J mice were fed a standard chow (NC), a CL diet (CL), or a CL diet containing 0.003% β-cry...
<p>Control wild-type and <i>db/db</i> (left panels) or <i>ob/ob</i> (right panels) male mice on the ...
<p>Gene expression of A) <i>Acaca</i>, B) <i>Adh1</i>, C) <i>Cpt1a</i>, D) <i>Cyp2e1</i>, E) <i>Dgat...
<p>Total RNA was extracted from liver tissues of male wild type or <i>Tet-mev-1</i> mice (<i>+ROS</i...
<p><b>activates enzymes in BA synthesis.</b> (A) mRNA levels of cholesterol 7α-hydroxylase (Cyp7a1) ...
ICR mice were fed with either a CFD or control diet for 25 weeks. Mice were weighed every week. (A) ...
Histone deacetylases (HDACs) are involved in the regulation of cholesterol 7alpha-hydroxylase gene (...
<p>(A) mRNA expression levels of <i>Cyp7a1</i>, <i>Cyp8b1, Cyp27a1, Shp</i>, <i>Fxr</i>, <i>Pgc-1α</...
<p>The C16:1/C16:0, C18:1/C18:0 (A) and C18:0/C16:0 (B) ratios were calculated, based on data obtain...