Body and liver weights in Cftr knockout, ΔF508 Cftr and control mice, fed a control diet or a cholic acid (CA) containing diet for 3 weeks.

<p>Body weight (A, B), absolute liver weight (C,D) and relative liver weight reported as a percentage of the body weight (E, F) in <i>Cftr</i> knockout mice (<i>Cftr</i>^<i>-/-</i>, panels A. C and E) or ΔF508 <i>Cftr</i> mice (<i>Cftr</i>^tm1EUR, panels B, D and F) and their respective control littermates (<i>Cftr</i>^<i>+/+</i>), after a control or 0.5%-CA (wt/wt) chow diet for three weeks. Data are presented as means ± SEM of N = 5–7 mice per group. *P-value<0.05.