(A) Waterfall plot of detailed mutation information of top 20 genes in each sample, with various color annotations to distinguish different mutation types. (B-D) According to different classification categories, missense mutation, SNP, and C > T mutation accounted for the overwhelming majority. (E) The total mutation number in each sample. (F) Box plots of each variant classification in each sample. (G) Top 10 mutated genes in CRC. SNP, single nucleotide polymorphism; SNV, single nucleotide variants. (TIF)</p
<p>(A) Pie charts of hypermutation per IgV<sub>H</sub> region for indicated Ramos B cell transductan...
Single nucleotide polymorphisms (SNPs) are the most common form of human genetic variation, with mil...
Only coding non-silent somatic mutations are considered. (A) Mutation rates (top panel), top mutated...
Somatic mutations were determined using paired OCSCC tumor/somatic DNA samples (n = 25), and defined...
<p>(A) Sequencing analysis workflow. Sequence alignment files underwent local-realignment around Ind...
<p>(A) A dynastic tree illustrating the relationship between mother, daughter, and granddaughter clo...
A) Number of mutated samples by gene according to the described mutation filtering protocol. Only re...
<p><b>(a)</b> Per-individual numbers, sorted from high to low, of somatic mutations falling in ZF po...
<p>Gene breakpoint frequencies (red bars) were based on the analysis of 352 CRC samples and gene mut...
a. The graphical summary of somatic mutations of the 4 genes in molecular subtypes. All of the 190 t...
<p>Mutations in different genes (rows) are indicated for each CRC sample (columns). A grey square in...
<p>(A) Proportion of subjects with mutations identified vs. remaining as persistent NMI. (B) Proport...
Statistical analysis of pathogenicity of somatic mutations in cancer Recent large-scale sequencing s...
<p>Coding mutations in known cancer genes (A) and candidate genes (B) are indicated with different c...
<p>A) Plotted on the x-axis is the observed number of coding sequence (CDS) mutations in each of the...
<p>(A) Pie charts of hypermutation per IgV<sub>H</sub> region for indicated Ramos B cell transductan...
Single nucleotide polymorphisms (SNPs) are the most common form of human genetic variation, with mil...
Only coding non-silent somatic mutations are considered. (A) Mutation rates (top panel), top mutated...
Somatic mutations were determined using paired OCSCC tumor/somatic DNA samples (n = 25), and defined...
<p>(A) Sequencing analysis workflow. Sequence alignment files underwent local-realignment around Ind...
<p>(A) A dynastic tree illustrating the relationship between mother, daughter, and granddaughter clo...
A) Number of mutated samples by gene according to the described mutation filtering protocol. Only re...
<p><b>(a)</b> Per-individual numbers, sorted from high to low, of somatic mutations falling in ZF po...
<p>Gene breakpoint frequencies (red bars) were based on the analysis of 352 CRC samples and gene mut...
a. The graphical summary of somatic mutations of the 4 genes in molecular subtypes. All of the 190 t...
<p>Mutations in different genes (rows) are indicated for each CRC sample (columns). A grey square in...
<p>(A) Proportion of subjects with mutations identified vs. remaining as persistent NMI. (B) Proport...
Statistical analysis of pathogenicity of somatic mutations in cancer Recent large-scale sequencing s...
<p>Coding mutations in known cancer genes (A) and candidate genes (B) are indicated with different c...
<p>A) Plotted on the x-axis is the observed number of coding sequence (CDS) mutations in each of the...
<p>(A) Pie charts of hypermutation per IgV<sub>H</sub> region for indicated Ramos B cell transductan...
Single nucleotide polymorphisms (SNPs) are the most common form of human genetic variation, with mil...
Only coding non-silent somatic mutations are considered. (A) Mutation rates (top panel), top mutated...