Analyses of somatic mutation profiles in CRC samples.

(A) Waterfall plot of detailed mutation information of top 20 genes in each sample, with various color annotations to distinguish different mutation types. (B-D) According to different classification categories, missense mutation, SNP, and C > T mutation accounted for the overwhelming majority. (E) The total mutation number in each sample. (F) Box plots of each variant classification in each sample. (G) Top 10 mutated genes in CRC. SNP, single nucleotide polymorphism; SNV, single nucleotide variants. (TIF)