<p>Gene breakpoint frequencies (red bars) were based on the analysis of 352 CRC samples and gene mutation frequencies (blue bars) on the analysis of 204 samples. Genes marked with a “*” indicate a pool of genes that share probe(s) associated with chromosomal breakpoints: the <i>PCMTD2*</i> pool also includes <i>LINC00266-1; PARK2*</i> also includes <i>PACRG</i>; <i>ZNF337*</i> also includes <i>NCOR1P1</i>, <i>FAM182A</i>, <i>FAM182B</i>, <i>FRG1B</i>, <i>MIR663A</i>, <i>MLLT10P1</i>; <i>CD99*</i> also includes <i>XG</i>; <i>PARP8*</i> also includes <i>EMB</i>.</p
<p>Genes and samples were clustered independently by hierarchical clustering. Rows represent genes, ...
<p>Amplification regions are shown in red; deletion regions are shown in blue; regions with no signi...
<p>The 48 genes among the 141 predicted cancer genes known in the literature as diagnostic or progno...
<p>The nodes comprise both gene breakpoints (red outline) and gene mutations (blue outline). Edges (...
<p>(A) Co-clustering matrix of CRC samples generated by NBS analysis. The matrix color intensity rep...
(A) Waterfall plot of detailed mutation information of top 20 genes in each sample, with various col...
Background: Cancer is caused by somatic DNA alterations such as gene point mutations, DNA copy numbe...
Cancer is caused by somatic DNA alterations such as gene point mutations, DNA copy number aberration...
<div><p>Background</p><p>Cancer is caused by somatic DNA alterations such as gene point mutations, D...
<p>The relative mutation frequencies of <i>PBRM1</i>, <i>BAP1</i> and <i>KDM5C</i> in the three CCRC...
Background Cancer is caused by somatic DNA alterations such as gene point mutations, DNA copy number...
<p>We performed exome sequencing analysis of germline DNA from 96 independent familial CRC cases. In...
<p><i>Abbreviations:</i> chr, chromosome; fr, frequency; Hap, haplotype. Haplotypes in chr11 is shap...
<p>(<b>A</b>) Genomic DNA isolated from EGFP-negative and -positive cells carrying experimental cons...
<p>Bootscan plots are shown for <b>(A)</b> CRF11_cpx, <b>(B)</b> CRF13_cpx, <b>(C)</b> CRF18_cpx and...
<p>Genes and samples were clustered independently by hierarchical clustering. Rows represent genes, ...
<p>Amplification regions are shown in red; deletion regions are shown in blue; regions with no signi...
<p>The 48 genes among the 141 predicted cancer genes known in the literature as diagnostic or progno...
<p>The nodes comprise both gene breakpoints (red outline) and gene mutations (blue outline). Edges (...
<p>(A) Co-clustering matrix of CRC samples generated by NBS analysis. The matrix color intensity rep...
(A) Waterfall plot of detailed mutation information of top 20 genes in each sample, with various col...
Background: Cancer is caused by somatic DNA alterations such as gene point mutations, DNA copy numbe...
Cancer is caused by somatic DNA alterations such as gene point mutations, DNA copy number aberration...
<div><p>Background</p><p>Cancer is caused by somatic DNA alterations such as gene point mutations, D...
<p>The relative mutation frequencies of <i>PBRM1</i>, <i>BAP1</i> and <i>KDM5C</i> in the three CCRC...
Background Cancer is caused by somatic DNA alterations such as gene point mutations, DNA copy number...
<p>We performed exome sequencing analysis of germline DNA from 96 independent familial CRC cases. In...
<p><i>Abbreviations:</i> chr, chromosome; fr, frequency; Hap, haplotype. Haplotypes in chr11 is shap...
<p>(<b>A</b>) Genomic DNA isolated from EGFP-negative and -positive cells carrying experimental cons...
<p>Bootscan plots are shown for <b>(A)</b> CRF11_cpx, <b>(B)</b> CRF13_cpx, <b>(C)</b> CRF18_cpx and...
<p>Genes and samples were clustered independently by hierarchical clustering. Rows represent genes, ...
<p>Amplification regions are shown in red; deletion regions are shown in blue; regions with no signi...
<p>The 48 genes among the 141 predicted cancer genes known in the literature as diagnostic or progno...