A. Graphs displayed the mutation frequency of those genes mutated in more than 2.5% of patients for all and each breast cancer subtype. B. Heat map of the mutation frequency and the functions of the identified genes for each breast cancer subtypes. The percentage of mutated cases is displayed in the legend.</p
A major goal of cancer sequencing projects is to identify genetic alterations that determine clinica...
From a simulated tumor, we randomly sampled 1000 cells and their mutation profile is presented as a ...
<p>The heatmap reflects the significance of cancer-type-specific mutation density of each domain ins...
a. The graphical summary of somatic mutations of the 4 genes in molecular subtypes. All of the 190 t...
Mutation frequency within each cancer type ranges from light red (0%) to dark red (≥ 10% of samples)...
A) Recurrent driver somatic mutations and copy number variations identified in matched primary and m...
<p>A summary chart of all mutations in each group displays genes across in rows and patient tumors d...
<p>A) Heatmap of number of variants per tumour group. On the y-axis the different primary tumour sit...
The heatmap shows the top 30 most frequently mutated genes in all the TCGA samples. Y-axis indicates...
(A) Distribution of common breast cancer mutations including PIK3CA (left), TP53 (middle), and TTN (...
<p>The heatmap shows genes (rows) and tumors (columns) with mutations (blue). The number of events p...
<p>Mutation plots showing the amount of genes that need to be sequenced (y-axis) in order to find a ...
Abstract Breast cancer is a complex molecular disease comprising several biological subtypes. Howeve...
A. Flow chart of the study, in which the METABRIC dataset was used to identify breast cancer mutated...
<p>Distribution of the number of mutations according to mutational signatures in HR+/HER2− metastati...
A major goal of cancer sequencing projects is to identify genetic alterations that determine clinica...
From a simulated tumor, we randomly sampled 1000 cells and their mutation profile is presented as a ...
<p>The heatmap reflects the significance of cancer-type-specific mutation density of each domain ins...
a. The graphical summary of somatic mutations of the 4 genes in molecular subtypes. All of the 190 t...
Mutation frequency within each cancer type ranges from light red (0%) to dark red (≥ 10% of samples)...
A) Recurrent driver somatic mutations and copy number variations identified in matched primary and m...
<p>A summary chart of all mutations in each group displays genes across in rows and patient tumors d...
<p>A) Heatmap of number of variants per tumour group. On the y-axis the different primary tumour sit...
The heatmap shows the top 30 most frequently mutated genes in all the TCGA samples. Y-axis indicates...
(A) Distribution of common breast cancer mutations including PIK3CA (left), TP53 (middle), and TTN (...
<p>The heatmap shows genes (rows) and tumors (columns) with mutations (blue). The number of events p...
<p>Mutation plots showing the amount of genes that need to be sequenced (y-axis) in order to find a ...
Abstract Breast cancer is a complex molecular disease comprising several biological subtypes. Howeve...
A. Flow chart of the study, in which the METABRIC dataset was used to identify breast cancer mutated...
<p>Distribution of the number of mutations according to mutational signatures in HR+/HER2− metastati...
A major goal of cancer sequencing projects is to identify genetic alterations that determine clinica...
From a simulated tumor, we randomly sampled 1000 cells and their mutation profile is presented as a ...
<p>The heatmap reflects the significance of cancer-type-specific mutation density of each domain ins...