Distribution of the number of mutations according to mutational signatures in HR+/HER2− metastatic and primary (TCGA) breast tumors. | ORKG Ask

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Distribution of mutations according to their functional category among the validation cohort.

Mariam Ibáñez (588131)
José Carbonell-Caballero (1888831)
Esperanza Such (588128)
Luz García-Alonso (1888822)
Alessandro Liquori (5843183)
María López-Pavía (588130)
Marta Llop (588132)
Carmen Alonso (375741)
Eva Barragán (588127)
Inés Gómez-Seguí (588126)
Alexander Neef (257267)
David Hervás (457877)
Pau Montesinos (588135)
Guillermo Sanz (3492494)
Miguel Angel Sanz (202855)
Joaquín Dopazo (1888828)
José Cervera (243824)

October 2018

Distribution of mutations according to their functional category among the validation cohort.</p

Mutational profile by breast cancer subtype, and association with biological functions.

Sara Morcillo-Garcia (6593528)
Maria del Mar Noblejas-Lopez (6593531)
Cristina Nieto-Jimenez (6593534)
Javier Perez-Peña (6593537)
Miriam Nuncia-Cantarero (6019322)
Balázs Győrffy (110652)
Eitan Amir (525324)
Atanasio Pandiella (195056)
Eva M. Galan-Moya (194053)
Alberto Ocana (2697079)

April 2019

A. Graphs displayed the mutation frequency of those genes mutated in more than 2.5% of patients for ...

Repertoire of genomic alterations in primary and metastatic HR+ HER2- breast cancer (BC).

Lorenzo Ferrando (6648539)
Andrea Vingiani (8204229)
Anna Garuti (212195)
Claudio Vernieri (9744243)
Antonino Belfiore (155199)
Luca Agnelli (207773)
Gianpaolo Dagrada (5754221)
Diana Ivanoiu (14322304)
Giuseppina Bonizzi (9528557)
Elisabetta Munzone (5958338)
Luana Lippolis (14322307)
Martina Dameri (10979993)
Francesco Ravera (12545903)
Marco Colleoni (6393845)
Giuseppe Viale (173594)
Luca Magnani (167833)
Alberto Ballestrero (212236)
Gabriele Zoppoli (201733)
Giancarlo Pruneri (384238)

January 2023

A) Recurrent driver somatic mutations and copy number variations identified in matched primary and m...

The distribution of somatic mutations in different breast cancer subtypes of the 313 breast cancer patients.

Guoli Li (291427)
Xinwu Guo (201033)
Ming Chen (115604)
Lili Tang (23345)
Hui Jiang (102809)
Julia X. Day (5746184)
Yueliang Xie (5746187)
Limin Peng (294273)
Xunxun Xu (804489)
Jinliang Li (75116)
Shouman Wang (3842485)
Zhi Xiao (4436815)
Lizhong Dai (3842488)
Jun Wang (5906)

September 2018

a. The graphical summary of somatic mutations of the 4 genes in molecular subtypes. All of the 190 t...

Distribution of somatic mutations for breast invasive carcinoma (BRCA) is similar by subtype and stage.

Ramu Anandakrishnan (294535)
Robin T. Varghese (6181574)
Nicholas A. Kinney (701768)
Harold R. Garner (6157)

March 2019

The estimated number of hits is identical for subsets of BRCA samples by (a) subtype and (b) stage.<...

Distribution of germline or somatic <i>BRCA1/2</i> variants in 507 breast cancer patients.

Xiaorong Zhong (2816683)
Zhengwei Dong (2816680)
Hua Dong (241097)
Jiayuan Li (448199)
Zuxiang Peng (2816674)
Ling Deng (713393)
Xuehua Zhu (258237)
Yun Sun (451368)
Xuesong Lu (2249827)
Fuxiao Shen (2816677)
Xinying Su (776388)
Liying Zhang (102453)
Yi Gu (237512)
Hong Zheng (151877)

June 2016

<p>Distribution of germline or somatic <i>BRCA1/2</i> variants in 507 breast cancer patients.</p

Distribution of pathogenic/likely pathogenic mutations with respect to family history, age at diagnosis and first cancer at diagnosis.

Pi-Lin Sung (4479589)
Kuo-Chang Wen (4479583)
Yi-Jen Chen (110805)
Ta-Chung Chao (526531)
Yi-Fang Tsai (526528)
Ling-Ming Tseng (526534)
Jian-Tai Timothy Qiu (4479586)
Kuan-Chong Chao (4479592)
Hua-Hsi Wu (751955)
Chi-Mu Chuang (3573335)
Peng-Hui Wang (329082)
Chi-Ying F. Huang (197633)

September 2017

<p>Distribution of pathogenic/likely pathogenic mutations with respect to family history, age at dia...

Distribution of pathogenic mutations reported out in first 3,000 patient samples referred for BRCAplus testing.

Hansook Kim Chong (212938)
Tao Wang (12008)
Hsiao-Mei Lu (258794)
Sara Seidler (564826)
Hong Lu (58784)
Steven Keiles (564827)
Elizabeth C. Chao (61495)
A. J. Stuenkel (564828)
Xiang Li (114679)
Aaron M. Elliott (564829)

May 2014

<p>Distribution of pathogenic mutations reported out in first 3,000 patient samples referred for BRC...

Distribution of mutations in the first 150 tumors genotyped in the molecular diagnostic lab.

Christine M. Lovly (169645)
Kimberly Brown Dahlman (169648)
Laurel E. Fohn (169652)
Zengliu Su (169656)
Dora Dias-Santagata (128565)
Donna J. Hicks (169659)
Donald Hucks (169663)
Elizabeth Berry (169667)
Charles Terry (169670)
MarKeesa Duke (169675)
Yingjun Su (169678)
Tammy Sobolik-Delmaire (169681)
Ann Richmond (169683)
Mark C. Kelley (169685)
Cindy L. Vnencak-Jones (169686)
A. John Iafrate (128597)
Jeffrey Sosman (169688)
William Pao (25938)

April 2012

<p>Left: distribution of all mutations. Right: distribution of V600 mutations. See <b><a href="http:...

Distribution of the number of mutations (<i>table</i>) and response to EGFR-targeted therapy (<i>pie-charts</i>) according to the number of molecular abnormalities within individual tumor samples.

Andrea Sartore-Bianchi (370139)
Federica Di Nicolantonio (5302)
Michele Nichelatti (370140)
Francesca Molinari (370141)
Sara De Dosso (370142)
Piercarlo Saletti (370143)
Miriam Martini (370144)
Tiziana Cipani (370145)
Giovanna Marrapese (370146)
Luca Mazzucchelli (370147)
Simona Lamba (370148)
Silvio Veronese (370149)
Milo Frattini (370150)
Alberto Bardelli (163979)
Salvatore Siena (336925)

February 2013

<p>Distribution of the number of mutations (<i>table</i>) and response to EGFR-targeted therapy (<i>...

Supplemental Figure 1 from Genetic Alterations Detected by Circulating Tumor DNA in HER2-Low Metastatic Breast Cancer

Whitney L. Hensing (16461978)
Lorenzo Gerratana (14955448)
Katherine Clifton (15054719)
Arielle J. Medford (16461981)
Marko Velimirovic (15030035)
Ami N. Shah (15030038)
Paolo D'Amico (16461984)
Carolina Reduzzi (16461987)
Qiang Zhang (16461990)
Charles S. Dai (16461993)
Elyssa N. Denault (16461996)
Nusayba A. Bagegni (16461999)
Mateusz Opyrchal (15073015)
Foluso O. Ademuyiwa (15054710)
Ron Bose (15045749)
Amir Behdad (16462002)
Cynthia X. Ma (15054767)
Aditya Bardia (16454483)
Massimo Cristofanilli (10431033)
Andrew A. Davis (15030032)

August 2023

Supplemental Figure 1. Mutation distribution for the PIK3CA gene in the overall study population div...

Distribution of TP53 and FGFR3 somatic mutations in relation to tumor morphology and histology.

Alessandro Apollo (3842275)
Valerio Ortenzi (2037904)
Cristian Scatena (2037901)
Katia Zavaglia (5768015)
Paolo Aretini (3577613)
Francesca Lessi (238026)
Sara Franceschi (3577601)
Sara Tomei (3441323)
Carlo Alberto Sepich (6236564)
Paolo Viacava (6236567)
Chiara Maria Mazzanti (3842278)
Antonio Giuseppe Naccarato (2037895)

January 2019

Distribution of TP53 and FGFR3 somatic mutations in relation to tumor morphology and histology.</p

Distribution of microRNA gene genetic variants and Odds ratio with 95% CI in breast cancer patients and control subjects.

Ali A. Alshatwi (303511)
Gowhar Shafi (332090)
Tarique N. Hasan (303512)
Naveed Ahmed Syed (332094)
Amal A. Al-Hazzani (332096)
Mohammed A. Alsaif (332099)
Abdulaziz A. Alsaif (332102)

February 2013

<p>Distribution of microRNA gene genetic variants and Odds ratio with 95% CI in breast cancer patien...

Distribution of mutations according to their functional category among the validation cohort.

Mariam Ibáñez (588131)
José Carbonell-Caballero (1888831)
Esperanza Such (588128)
Luz García-Alonso (1888822)
Alessandro Liquori (5843183)
María López-Pavía (588130)
Marta Llop (588132)
Carmen Alonso (375741)
Eva Barragán (588127)
Inés Gómez-Seguí (588126)
Alexander Neef (257267)
David Hervás (457877)
Pau Montesinos (588135)
Guillermo Sanz (3492494)
Miguel Angel Sanz (202855)
Joaquín Dopazo (1888828)
José Cervera (243824)

October 2018

Distribution of mutations according to their functional category among the validation cohort.</p

Mutational profile by breast cancer subtype, and association with biological functions.

Sara Morcillo-Garcia (6593528)
Maria del Mar Noblejas-Lopez (6593531)
Cristina Nieto-Jimenez (6593534)
Javier Perez-Peña (6593537)
Miriam Nuncia-Cantarero (6019322)
Balázs Győrffy (110652)
Eitan Amir (525324)
Atanasio Pandiella (195056)
Eva M. Galan-Moya (194053)
Alberto Ocana (2697079)

April 2019

A. Graphs displayed the mutation frequency of those genes mutated in more than 2.5% of patients for ...

Repertoire of genomic alterations in primary and metastatic HR+ HER2- breast cancer (BC).

Lorenzo Ferrando (6648539)
Andrea Vingiani (8204229)
Anna Garuti (212195)
Claudio Vernieri (9744243)
Antonino Belfiore (155199)
Luca Agnelli (207773)
Gianpaolo Dagrada (5754221)
Diana Ivanoiu (14322304)
Giuseppina Bonizzi (9528557)
Elisabetta Munzone (5958338)
Luana Lippolis (14322307)
Martina Dameri (10979993)
Francesco Ravera (12545903)
Marco Colleoni (6393845)
Giuseppe Viale (173594)
Luca Magnani (167833)
Alberto Ballestrero (212236)
Gabriele Zoppoli (201733)
Giancarlo Pruneri (384238)

January 2023

A) Recurrent driver somatic mutations and copy number variations identified in matched primary and m...

The distribution of somatic mutations in different breast cancer subtypes of the 313 breast cancer patients.

Guoli Li (291427)
Xinwu Guo (201033)
Ming Chen (115604)
Lili Tang (23345)
Hui Jiang (102809)
Julia X. Day (5746184)
Yueliang Xie (5746187)
Limin Peng (294273)
Xunxun Xu (804489)
Jinliang Li (75116)
Shouman Wang (3842485)
Zhi Xiao (4436815)
Lizhong Dai (3842488)
Jun Wang (5906)

September 2018

a. The graphical summary of somatic mutations of the 4 genes in molecular subtypes. All of the 190 t...

Distribution of germline or somatic <i>BRCA1/2</i> variants in 507 breast cancer patients.

Xiaorong Zhong (2816683)
Zhengwei Dong (2816680)
Hua Dong (241097)
Jiayuan Li (448199)
Zuxiang Peng (2816674)
Ling Deng (713393)
Xuehua Zhu (258237)
Yun Sun (451368)
Xuesong Lu (2249827)
Fuxiao Shen (2816677)
Xinying Su (776388)
Liying Zhang (102453)
Yi Gu (237512)
Hong Zheng (151877)

June 2016

<p>Distribution of germline or somatic <i>BRCA1/2</i> variants in 507 breast cancer patients.</p

Distribution of pathogenic/likely pathogenic mutations with respect to family history, age at diagnosis and first cancer at diagnosis.

Pi-Lin Sung (4479589)
Kuo-Chang Wen (4479583)
Yi-Jen Chen (110805)
Ta-Chung Chao (526531)
Yi-Fang Tsai (526528)
Ling-Ming Tseng (526534)
Jian-Tai Timothy Qiu (4479586)
Kuan-Chong Chao (4479592)
Hua-Hsi Wu (751955)
Chi-Mu Chuang (3573335)
Peng-Hui Wang (329082)
Chi-Ying F. Huang (197633)

September 2017

<p>Distribution of pathogenic/likely pathogenic mutations with respect to family history, age at dia...

Distribution of pathogenic mutations reported out in first 3,000 patient samples referred for BRCAplus testing.

Hansook Kim Chong (212938)
Tao Wang (12008)
Hsiao-Mei Lu (258794)
Sara Seidler (564826)
Hong Lu (58784)
Steven Keiles (564827)
Elizabeth C. Chao (61495)
A. J. Stuenkel (564828)
Xiang Li (114679)
Aaron M. Elliott (564829)

May 2014

<p>Distribution of pathogenic mutations reported out in first 3,000 patient samples referred for BRC...

Distribution of mutations in the first 150 tumors genotyped in the molecular diagnostic lab.

Christine M. Lovly (169645)
Kimberly Brown Dahlman (169648)
Laurel E. Fohn (169652)
Zengliu Su (169656)
Dora Dias-Santagata (128565)
Donna J. Hicks (169659)
Donald Hucks (169663)
Elizabeth Berry (169667)
Charles Terry (169670)
MarKeesa Duke (169675)
Yingjun Su (169678)
Tammy Sobolik-Delmaire (169681)
Ann Richmond (169683)
Mark C. Kelley (169685)
Cindy L. Vnencak-Jones (169686)
A. John Iafrate (128597)
Jeffrey Sosman (169688)
William Pao (25938)

April 2012

<p>Left: distribution of all mutations. Right: distribution of V600 mutations. See <b><a href="http:...

Distribution of the number of mutations (<i>table</i>) and response to EGFR-targeted therapy (<i>pie-charts</i>) according to the number of molecular abnormalities within individual tumor samples.

Andrea Sartore-Bianchi (370139)
Federica Di Nicolantonio (5302)
Michele Nichelatti (370140)
Francesca Molinari (370141)
Sara De Dosso (370142)
Piercarlo Saletti (370143)
Miriam Martini (370144)
Tiziana Cipani (370145)
Giovanna Marrapese (370146)
Luca Mazzucchelli (370147)
Simona Lamba (370148)
Silvio Veronese (370149)
Milo Frattini (370150)
Alberto Bardelli (163979)
Salvatore Siena (336925)

February 2013

<p>Distribution of the number of mutations (<i>table</i>) and response to EGFR-targeted therapy (<i>...

Supplemental Figure 1 from Genetic Alterations Detected by Circulating Tumor DNA in HER2-Low Metastatic Breast Cancer

Whitney L. Hensing (16461978)
Lorenzo Gerratana (14955448)
Katherine Clifton (15054719)
Arielle J. Medford (16461981)
Marko Velimirovic (15030035)
Ami N. Shah (15030038)
Paolo D'Amico (16461984)
Carolina Reduzzi (16461987)
Qiang Zhang (16461990)
Charles S. Dai (16461993)
Elyssa N. Denault (16461996)
Nusayba A. Bagegni (16461999)
Mateusz Opyrchal (15073015)
Foluso O. Ademuyiwa (15054710)
Ron Bose (15045749)
Amir Behdad (16462002)
Cynthia X. Ma (15054767)
Aditya Bardia (16454483)
Massimo Cristofanilli (10431033)
Andrew A. Davis (15030032)

August 2023

Supplemental Figure 1. Mutation distribution for the PIK3CA gene in the overall study population div...

Distribution of TP53 and FGFR3 somatic mutations in relation to tumor morphology and histology.

Alessandro Apollo (3842275)
Valerio Ortenzi (2037904)
Cristian Scatena (2037901)
Katia Zavaglia (5768015)
Paolo Aretini (3577613)
Francesca Lessi (238026)
Sara Franceschi (3577601)
Sara Tomei (3441323)
Carlo Alberto Sepich (6236564)
Paolo Viacava (6236567)
Chiara Maria Mazzanti (3842278)
Antonio Giuseppe Naccarato (2037895)

January 2019

Distribution of TP53 and FGFR3 somatic mutations in relation to tumor morphology and histology.</p

Distribution of microRNA gene genetic variants and Odds ratio with 95% CI in breast cancer patients and control subjects.

Ali A. Alshatwi (303511)
Gowhar Shafi (332090)
Tarique N. Hasan (303512)
Naveed Ahmed Syed (332094)
Amal A. Al-Hazzani (332096)
Mohammed A. Alsaif (332099)
Abdulaziz A. Alsaif (332102)

February 2013

<p>Distribution of microRNA gene genetic variants and Odds ratio with 95% CI in breast cancer patien...

Distribution of mutations according to their functional category among the validation cohort.

Mariam Ibáñez (588131)
José Carbonell-Caballero (1888831)
Esperanza Such (588128)
Luz García-Alonso (1888822)
Alessandro Liquori (5843183)
María López-Pavía (588130)
Marta Llop (588132)
Carmen Alonso (375741)
Eva Barragán (588127)
Inés Gómez-Seguí (588126)
Alexander Neef (257267)
David Hervás (457877)
Pau Montesinos (588135)
Guillermo Sanz (3492494)
Miguel Angel Sanz (202855)
Joaquín Dopazo (1888828)
José Cervera (243824)

October 2018

Distribution of mutations according to their functional category among the validation cohort.</p

Mutational profile by breast cancer subtype, and association with biological functions.

Sara Morcillo-Garcia (6593528)
Maria del Mar Noblejas-Lopez (6593531)
Cristina Nieto-Jimenez (6593534)
Javier Perez-Peña (6593537)
Miriam Nuncia-Cantarero (6019322)
Balázs Győrffy (110652)
Eitan Amir (525324)
Atanasio Pandiella (195056)
Eva M. Galan-Moya (194053)
Alberto Ocana (2697079)

April 2019

A. Graphs displayed the mutation frequency of those genes mutated in more than 2.5% of patients for ...