<p>Shown are plots of the absolute value of expression level fold-change between median expression levels of homozygote classes for significant associations (permutation threshold 0.01) for each pairwise combination of populations. Within a panel, deviating from the 1 to 1 line (lower left to upper right) indicates differences in expression level fold-change (effect size) on log<sub>2</sub> scale in the two populations being compared.</p
<p>Ratios of significant (FDR < 0.05) up- vs. down-regulated monocyte expression change are plotted,...
<p>Panel A shows a heat map of the 25% (7685 probes) most variable genes in the dataset for all samp...
<p>Scatter plots by log<sub>2</sub> fold gene expression changes in LSK, CMP, GMP and MEP cells comp...
<p>−log<sub>10</sub> of the p-value is plotted against distance measured in base pairs from the asso...
<p>−log<sub>10</sub> of the p-value is plotted against distance measured in base pairs from the asso...
<p>Shown are plots of rho for significant associations (permutation threshold 0.01) for each pairwis...
<p>The effects on measured log<sub>2</sub> transformed (L2T) gene expression levels per mismatch all...
<p>The heterogeneity of SNP effects across the five populations is measured by log<sub>10</sub>[BF<s...
<p>SNP rs6006800 and the SNPs in LD are labeled by the purple triangles in the top panel. They displ...
<p>Distribution of the number of groups for which there is a clear change in the expression level of...
<p>PcG regions, plotted by initial span (x-axis) and monocyte to DC differentiation-linked fold chan...
<p>Plotted here are (i.e., the -fold expression changes) vs. (i.e., the maximum within-condition e...
<p>The <i>x</i>-axis shows the fold change (log<sub>2</sub> ratio) in gene expression in TN1 populat...
<p><b>(a) Relationship between GWAS p-value for a SNP, and coexpression scores of individual promote...
<p>(A) Number of activating (‘A’) and repressing (‘R’) TFBSs containing SNPs with purely positive in...
<p>Ratios of significant (FDR < 0.05) up- vs. down-regulated monocyte expression change are plotted,...
<p>Panel A shows a heat map of the 25% (7685 probes) most variable genes in the dataset for all samp...
<p>Scatter plots by log<sub>2</sub> fold gene expression changes in LSK, CMP, GMP and MEP cells comp...
<p>−log<sub>10</sub> of the p-value is plotted against distance measured in base pairs from the asso...
<p>−log<sub>10</sub> of the p-value is plotted against distance measured in base pairs from the asso...
<p>Shown are plots of rho for significant associations (permutation threshold 0.01) for each pairwis...
<p>The effects on measured log<sub>2</sub> transformed (L2T) gene expression levels per mismatch all...
<p>The heterogeneity of SNP effects across the five populations is measured by log<sub>10</sub>[BF<s...
<p>SNP rs6006800 and the SNPs in LD are labeled by the purple triangles in the top panel. They displ...
<p>Distribution of the number of groups for which there is a clear change in the expression level of...
<p>PcG regions, plotted by initial span (x-axis) and monocyte to DC differentiation-linked fold chan...
<p>Plotted here are (i.e., the -fold expression changes) vs. (i.e., the maximum within-condition e...
<p>The <i>x</i>-axis shows the fold change (log<sub>2</sub> ratio) in gene expression in TN1 populat...
<p><b>(a) Relationship between GWAS p-value for a SNP, and coexpression scores of individual promote...
<p>(A) Number of activating (‘A’) and repressing (‘R’) TFBSs containing SNPs with purely positive in...
<p>Ratios of significant (FDR < 0.05) up- vs. down-regulated monocyte expression change are plotted,...
<p>Panel A shows a heat map of the 25% (7685 probes) most variable genes in the dataset for all samp...
<p>Scatter plots by log<sub>2</sub> fold gene expression changes in LSK, CMP, GMP and MEP cells comp...