Positive and negative influence of SNPs from the study population.

<p>(A) Number of activating (‘A’) and repressing (‘R’) TFBSs containing SNPs with purely positive influence on gene expression (red), purely negative influence (blue), and with alternating sign (green). (B) Distribution of Δ<i>P</i> values for activating and repressing TFBSs and for different signs of SNP influence on expression. The labels and colors have the same meaning as in A. The dots show outliers.