Tumor growth of H1299 p53β and H1299 p53γ cells.

<p>(<b>A</b>) H1299 <i>in vivo</i> s.c. tumors were measured in 3 independent experiments. In total: p53β⁺ tumors n = 17; p53γ⁺ tumors n = 17; Control vector (Ctrl; tdTomato⁺) n = 20. The tumor sizes of p53β⁺ and p53γ⁺ tumors were compared to ctrl tumors using Students t-test. * <i>P</i>-value<0.05, ** <i>P</i>-value<0.001, *** <i>P</i>-value<0.0001. Insert (top left corner) shows tumor measurements of tumors that were injected without matrigel. Error bars: standard error of mean. (<b>B</b>) Immunohistochemistry of p53 (DO-7) of s.c. tumors. Top: p53-negative vector control tumor (Ctrl). Middle: p53γ⁺ tumor. Bottom: p53β⁺ tumor. Scale bar left images 1 mm, right images 50 µm, middle insert 10 µm.