<p>(A) Western blot of samples from the infarct core and the peri-infarct area from SA4503 (0.5 mg/kg s.c.; n = 7) and vehicle treated rats (n = 6) and respective densitometric analyses (mean±SD, *p<0.05, t-test) at day 7 following MCAO. Note that each lane represents an individual animal. (B) Average Iba1 immunoreactivity in the ischemic hemisphere of vehicle and SA4503 rats on day 7 after tMCAo. Average Cy3 fluorescence intensity is presented per pixel (0 to 255) within the indicated areas considered as immunopositive Iba1, respectively (I/pixel; mean±s.d., n = 3 per treatment).</p
<p>Sham operated rat (SC) and MCAO rats were used for superoxide detection, protein expression studi...
<p>Representative photomicrographs showing Iba-1 immunostaining in cross-sections of proximal and di...
<p>SHAM rats without treatment were used as control. Representative Western blots are shown in figur...
<p>Representative Western blots of samples from the ischemic infarct core from SA4503 (0.5 mg/kg; n ...
<p>Cortical, subcortical and total integrated infarct areas and volumes in rats after permanent MCAo...
<p>Sig-1R immunoreactivity in a vehicle (<b>A</b>) and SA4503 (<b>B</b>) treated animal after MCAO. ...
<p>Data are expressed as means ±S. D., ##P < 0.01 vs. sham group, *P < 0.05, **P < 0.01 vs. model gr...
<p>(A) Infarct images using TTC staining at day 7 after MCAO; (B) Determination of infarct volume at...
<p>(a) Representative TTC stained sections of vehicle and MTA treated animals (30 mg/kg/twice daily,...
<p>Example control images obtained with a 20x objective, the magnification used for cell counting (s...
<p><b>A.</b> Representative ET<sub>B</sub>R and Sp1 immunostainings in the MCA on the occluded side ...
<p>representative photographs of brain slices; no infarct area detected in sham group. <b>B:</b> the...
<p>ISODATA determined core (red) tissue volume was used as the initial lesion volume. Final infarct ...
<p>AM1241, pioglitazone, or vehicle was given to rats from days 2 to 5 after a 60-min MCAo. Animals ...
<p>The sections were taken from the infarct regions of the ipsilateral hippocampus 1, 3, 6, 12 and 2...
<p>Sham operated rat (SC) and MCAO rats were used for superoxide detection, protein expression studi...
<p>Representative photomicrographs showing Iba-1 immunostaining in cross-sections of proximal and di...
<p>SHAM rats without treatment were used as control. Representative Western blots are shown in figur...
<p>Representative Western blots of samples from the ischemic infarct core from SA4503 (0.5 mg/kg; n ...
<p>Cortical, subcortical and total integrated infarct areas and volumes in rats after permanent MCAo...
<p>Sig-1R immunoreactivity in a vehicle (<b>A</b>) and SA4503 (<b>B</b>) treated animal after MCAO. ...
<p>Data are expressed as means ±S. D., ##P < 0.01 vs. sham group, *P < 0.05, **P < 0.01 vs. model gr...
<p>(A) Infarct images using TTC staining at day 7 after MCAO; (B) Determination of infarct volume at...
<p>(a) Representative TTC stained sections of vehicle and MTA treated animals (30 mg/kg/twice daily,...
<p>Example control images obtained with a 20x objective, the magnification used for cell counting (s...
<p><b>A.</b> Representative ET<sub>B</sub>R and Sp1 immunostainings in the MCA on the occluded side ...
<p>representative photographs of brain slices; no infarct area detected in sham group. <b>B:</b> the...
<p>ISODATA determined core (red) tissue volume was used as the initial lesion volume. Final infarct ...
<p>AM1241, pioglitazone, or vehicle was given to rats from days 2 to 5 after a 60-min MCAo. Animals ...
<p>The sections were taken from the infarct regions of the ipsilateral hippocampus 1, 3, 6, 12 and 2...
<p>Sham operated rat (SC) and MCAO rats were used for superoxide detection, protein expression studi...
<p>Representative photomicrographs showing Iba-1 immunostaining in cross-sections of proximal and di...
<p>SHAM rats without treatment were used as control. Representative Western blots are shown in figur...