<p>Representative Western blots of samples from the ischemic infarct core from SA4503 (0.5 mg/kg; n = 4) and vehicle treated (n = 4) rats at day 7 following MCAO. For densitometric analysis (mean±SD) n = 8 rats were included for each treatment group. Each lane represents an individual animal.</p
<p>Hemotoxylin-eosin stained coronal sections scanned at 20x objective. The animal with the MCAo + A...
<p>The rats in saline groups were combined for analysis, as they were not statistically different. (...
<p>Rats treated with NH<sub>4</sub>Cl in drinking water for 12 hrs, 4 or 7 days, n = 6 animals/ grou...
<p>(A) Western blot of samples from the infarct core and the peri-infarct area from SA4503 (0.5 mg/k...
<p>Sig-1R immunoreactivity in a vehicle (<b>A</b>) and SA4503 (<b>B</b>) treated animal after MCAO. ...
<p>representative photographs of brain slices; no infarct area detected in sham group. <b>B:</b> the...
<p>Data are expressed as means ±S. D., ##P < 0.01 vs. sham group, *P < 0.05, **P < 0.01 vs. model gr...
<p>(A) Infarct images using TTC staining at day 7 after MCAO; (B) Determination of infarct volume at...
<p>ISODATA determined core (red) tissue volume was used as the initial lesion volume. Final infarct ...
<p>Sham operated rat (SC) and MCAO rats were used for superoxide detection, protein expression studi...
<p>Cortical, subcortical and total integrated infarct areas and volumes in rats after permanent MCAo...
<p>A, B: Photographs of coronal brain sections of rats in control group (A) and 24h group (B) with 2...
<p>Treatments were administered intravenously (saline vehicle, or R18 and R18D at 300 nmol/kg) 30 mi...
<p>(<b>A</b>) Infarct volume from vehicle (saline; n = 8) and SA4503 treated (0.5 mg/kg; n = 8) rats...
<p>Representative coronal slices obtain with T<sub>2</sub>-weighting: <b>A</b>. at D1 <b>B</b>. at D...
<p>Hemotoxylin-eosin stained coronal sections scanned at 20x objective. The animal with the MCAo + A...
<p>The rats in saline groups were combined for analysis, as they were not statistically different. (...
<p>Rats treated with NH<sub>4</sub>Cl in drinking water for 12 hrs, 4 or 7 days, n = 6 animals/ grou...
<p>(A) Western blot of samples from the infarct core and the peri-infarct area from SA4503 (0.5 mg/k...
<p>Sig-1R immunoreactivity in a vehicle (<b>A</b>) and SA4503 (<b>B</b>) treated animal after MCAO. ...
<p>representative photographs of brain slices; no infarct area detected in sham group. <b>B:</b> the...
<p>Data are expressed as means ±S. D., ##P < 0.01 vs. sham group, *P < 0.05, **P < 0.01 vs. model gr...
<p>(A) Infarct images using TTC staining at day 7 after MCAO; (B) Determination of infarct volume at...
<p>ISODATA determined core (red) tissue volume was used as the initial lesion volume. Final infarct ...
<p>Sham operated rat (SC) and MCAO rats were used for superoxide detection, protein expression studi...
<p>Cortical, subcortical and total integrated infarct areas and volumes in rats after permanent MCAo...
<p>A, B: Photographs of coronal brain sections of rats in control group (A) and 24h group (B) with 2...
<p>Treatments were administered intravenously (saline vehicle, or R18 and R18D at 300 nmol/kg) 30 mi...
<p>(<b>A</b>) Infarct volume from vehicle (saline; n = 8) and SA4503 treated (0.5 mg/kg; n = 8) rats...
<p>Representative coronal slices obtain with T<sub>2</sub>-weighting: <b>A</b>. at D1 <b>B</b>. at D...
<p>Hemotoxylin-eosin stained coronal sections scanned at 20x objective. The animal with the MCAo + A...
<p>The rats in saline groups were combined for analysis, as they were not statistically different. (...
<p>Rats treated with NH<sub>4</sub>Cl in drinking water for 12 hrs, 4 or 7 days, n = 6 animals/ grou...