<p>The evolution of (A) viral diversity, <i>d<sub>G</sub></i>, (B) divergence, <i>d<sub>S</sub></i>, and (C) average fitness, <i>f</i>, with generations predicted by our simulations for different population sizes, <i>C</i>. Each cell is assumed to be infected with <i>M</i> = 3 virions. Error bars represent standard deviations.</p
We describe a stochastic virus evolutionmodel representing genomic diversification and within-host s...
<p>Dynamics of divergence and diversity when imposing a greater level of fitness for certain types o...
International audienceHigh-throughput sequencing has opened the route for a deep assessment of withi...
<p>The evolution of (A) viral diversity, <i>d<sub>G</sub></i>, (B) divergence, <i>d<sub>S</sub></i>,...
<p>The evolution of viral diversity, <i>d<sub>G</sub></i>, with generations predicted by our simulat...
<p>(A) The frequencies of proviral genomes in different Hamming classes at various times (generation...
<p>The time-dependent solution of the evolutionary virus dynamics simulation is presented (please no...
<p>Each point is the mean (<i>n</i> = 3, ± standard error of the mean) change in log<sub>10</sub> fi...
a<p>The mutation frequency is the average of ten simulations and is expressed as the number of mutat...
Panel (a) shows the noisy behaviour of three genetic diversity statistics (y-axis) from an individua...
<p>Each plotted point represents a Ti value calculated as the average fitness of a pair of recombina...
<p>Error bars denote the standard error of three separate simulations for each sampling time point.<...
<p>Comparison of two parental viruses IAB TrD and IE 68U201 and four chimeric viruses, IAB/IE/IAB, I...
<p>Curves indicate the prediction obtained using log<sub>10 </sub><i>a</i> = 2.387, <i>b</i> = 3.744...
<p>(A) Number of core CDSs depending on the number of genomes sampled. (B) Number of strain-specific...
We describe a stochastic virus evolutionmodel representing genomic diversification and within-host s...
<p>Dynamics of divergence and diversity when imposing a greater level of fitness for certain types o...
International audienceHigh-throughput sequencing has opened the route for a deep assessment of withi...
<p>The evolution of (A) viral diversity, <i>d<sub>G</sub></i>, (B) divergence, <i>d<sub>S</sub></i>,...
<p>The evolution of viral diversity, <i>d<sub>G</sub></i>, with generations predicted by our simulat...
<p>(A) The frequencies of proviral genomes in different Hamming classes at various times (generation...
<p>The time-dependent solution of the evolutionary virus dynamics simulation is presented (please no...
<p>Each point is the mean (<i>n</i> = 3, ± standard error of the mean) change in log<sub>10</sub> fi...
a<p>The mutation frequency is the average of ten simulations and is expressed as the number of mutat...
Panel (a) shows the noisy behaviour of three genetic diversity statistics (y-axis) from an individua...
<p>Each plotted point represents a Ti value calculated as the average fitness of a pair of recombina...
<p>Error bars denote the standard error of three separate simulations for each sampling time point.<...
<p>Comparison of two parental viruses IAB TrD and IE 68U201 and four chimeric viruses, IAB/IE/IAB, I...
<p>Curves indicate the prediction obtained using log<sub>10 </sub><i>a</i> = 2.387, <i>b</i> = 3.744...
<p>(A) Number of core CDSs depending on the number of genomes sampled. (B) Number of strain-specific...
We describe a stochastic virus evolutionmodel representing genomic diversification and within-host s...
<p>Dynamics of divergence and diversity when imposing a greater level of fitness for certain types o...
International audienceHigh-throughput sequencing has opened the route for a deep assessment of withi...