Simulations for the variation in core, strain-specific and pan-genome fractions over the number of genomes.

<p>(A) Number of core CDSs depending on the number of genomes sampled. (B) Number of strain-specific CDSs depending on the number of genomes sampled. (C) Pan-genome size (CDSs) depending on the number of genomes sampled. In all cases, genomes were sampled with 200 replicates. Black dots indicate the mean of the calculated values, while grey shades indicate the first and third quartile.