Mean values for random CIS formation (1000 IS) determined either with computer simulations or mathematically.

<p>Simulations were performed with 50000 runs each. g, haploid size of the human genome: 3.12 x 10⁶kb; <i>d</i>_n, genomic window size [kb] for CIS of n^th order: <i>d</i>₂ = 30, <i>d</i>₃ = 50, and <i>d</i>₄ = 100; <i>n</i>_is, number of (assumed) sampled integration sites: 1000.