<p>The random probability of CTCF overlapping was calculated based on the more than 10,000 simulated numbers versus the observed numbers in each category of CTCF-clusters. Genomic DNA segments of the same number and size as the CTCF-defined loci were randomly extracted from the human genome assembly (hg19) as background.</p
a<p>Genomic coordinates in hg19 assembly. The genome was simply partitioned into nonoverlapping 10 k...
<p>(A) Circos map of the whole-genome chromatin domains, associated CTCF-binding sites, DNaseI HS, a...
<div><p>(A) Results from Structure under different assumptions about the number of clusters (<i>K</i...
A prime goal in systems biology is the comprehensive use of existing high-throughput genomic dataset...
<p>4 RCC GWAS loci overlapped with 6 HIF ChIP-seq peaks. <b>A)</b> To assess the significance of thi...
<p>(A) Genome-wide distribution of CTCF-binding sites relative to cell type. Total number of CTCF-bi...
Additional files accompanying the study of experimental and predicted CTCF loops in human cell lines...
<p>A. Flow chart indicating the overall design of the experiment. CTCF binding was identified and qu...
<p>(A) Three different clonal lineages, represented as Cluster A, B and C, were identified based on ...
<p>(A) Map showing structure of typical <i>rDNA</i> repeat unit. NTS = non-transcribed spacer, ETS...
<p>(A) Cumulative number of CTCF-binding sites within replicating zones. The cumulative normalized n...
SummaryThe “CTCF code” hypothesis posits that CTCF pleiotropic functions are driven by recognition o...
The “CTCF code” hypothesis posits that CTCF pleiotropic functions are driven by recognition of diver...
<p>(A) IF/FISH on representative Kc167 cell nuclei depleted of Brown (control), CAL1, or HP1a. Heter...
<p>(A) Filtering strategy for testable CTCF binding sites. A number of binding sites were excluded f...
a<p>Genomic coordinates in hg19 assembly. The genome was simply partitioned into nonoverlapping 10 k...
<p>(A) Circos map of the whole-genome chromatin domains, associated CTCF-binding sites, DNaseI HS, a...
<div><p>(A) Results from Structure under different assumptions about the number of clusters (<i>K</i...
A prime goal in systems biology is the comprehensive use of existing high-throughput genomic dataset...
<p>4 RCC GWAS loci overlapped with 6 HIF ChIP-seq peaks. <b>A)</b> To assess the significance of thi...
<p>(A) Genome-wide distribution of CTCF-binding sites relative to cell type. Total number of CTCF-bi...
Additional files accompanying the study of experimental and predicted CTCF loops in human cell lines...
<p>A. Flow chart indicating the overall design of the experiment. CTCF binding was identified and qu...
<p>(A) Three different clonal lineages, represented as Cluster A, B and C, were identified based on ...
<p>(A) Map showing structure of typical <i>rDNA</i> repeat unit. NTS = non-transcribed spacer, ETS...
<p>(A) Cumulative number of CTCF-binding sites within replicating zones. The cumulative normalized n...
SummaryThe “CTCF code” hypothesis posits that CTCF pleiotropic functions are driven by recognition o...
The “CTCF code” hypothesis posits that CTCF pleiotropic functions are driven by recognition of diver...
<p>(A) IF/FISH on representative Kc167 cell nuclei depleted of Brown (control), CAL1, or HP1a. Heter...
<p>(A) Filtering strategy for testable CTCF binding sites. A number of binding sites were excluded f...
a<p>Genomic coordinates in hg19 assembly. The genome was simply partitioned into nonoverlapping 10 k...
<p>(A) Circos map of the whole-genome chromatin domains, associated CTCF-binding sites, DNaseI HS, a...
<div><p>(A) Results from Structure under different assumptions about the number of clusters (<i>K</i...