Pan and core genome size.

<p>The discovery order of genomes was permuted 100 times with the total number of genes discovered shown in upper series, and number of core genes below. The middle series considers genes to be core if they are present in at least <i>n</i>−2 of the genomes (extended core). The bottom series considers them to be core only if present in every strain (strict core). Fitted lines for core homology groups are <i>F</i>_<i>c</i>(<i>n</i>) = <i>κ</i>_<i>c</i> exp[−<i>n</i>/<i>τ</i>_<i>c</i>]+Ω where Ω is the estimated core genome size (dotted lines: 4,568 homology groups for the extended core, and 2,798 for the strict core). Boxes show medians, interquartile range, and full range of data.