<p>The time-dependent solution of the evolutionary virus dynamics simulation is presented (please note the log axes). The uninfected cell population is <i>x<sub>00</sub></i>, and the infected populations are presented by two lines, one showing the sum of all cells containing the <i>s<sub>1</sub></i> virus, , and the other containing the <i>s<sub>2</sub></i> virus,. The inset shows the infectivity of the two strains. We used the base-line model for this simulation. The parameters are <i>s<sub>1</sub> = 1, s<sub>2</sub> = 3, z = 0, Q = 0.1,, a = d = 1, N = 5.</i></p
<p>(a) A linear trade-off between the degree of global infection <i>G</i> (horizontal axis) and that...
<p>The time evolution of the various singly (solid lines) and doubly (dashed lines) infected cell (l...
We describe a stochastic virus evolutionmodel representing genomic diversification and within-host s...
<p>In all panels A–F, colored curves represent the pathogen population sizes of different virus stra...
<p>In the present work we consider three different models of pathogen evolution within an outbreak: ...
<p>(A) Full equilibrium (FE). (B) Shifting mosaic steady state (SMSS). A total of 10,000 patches wer...
<p>The evolution of (A) viral diversity, <i>d<sub>G</sub></i>, (B) divergence, <i>d<sub>S</sub></i>,...
<p>Proportion of the mutant is calculated as the number of hosts infected by the mutant parasite div...
Using an individual-based model, we simulate the behavior of two types of viruses, considering vario...
The following thesis explores the within-host population dynamics of viruses and their target cells ...
<p>We consider the dynamics of wildtype (WT) and variant (V) virus infection in a population of <i>K...
A new model of viral infection spreading in cell cultures is proposed taking into account virus muta...
<p>The evolution of viral diversity, <i>d<sub>G</sub></i>, with generations predicted by our simulat...
Phylogenetic trees can be used to study the evolution of any sequence that evolves, including viruse...
We consider two viral strains competing against each other within individual hosts (at cellular leve...
<p>(a) A linear trade-off between the degree of global infection <i>G</i> (horizontal axis) and that...
<p>The time evolution of the various singly (solid lines) and doubly (dashed lines) infected cell (l...
We describe a stochastic virus evolutionmodel representing genomic diversification and within-host s...
<p>In all panels A–F, colored curves represent the pathogen population sizes of different virus stra...
<p>In the present work we consider three different models of pathogen evolution within an outbreak: ...
<p>(A) Full equilibrium (FE). (B) Shifting mosaic steady state (SMSS). A total of 10,000 patches wer...
<p>The evolution of (A) viral diversity, <i>d<sub>G</sub></i>, (B) divergence, <i>d<sub>S</sub></i>,...
<p>Proportion of the mutant is calculated as the number of hosts infected by the mutant parasite div...
Using an individual-based model, we simulate the behavior of two types of viruses, considering vario...
The following thesis explores the within-host population dynamics of viruses and their target cells ...
<p>We consider the dynamics of wildtype (WT) and variant (V) virus infection in a population of <i>K...
A new model of viral infection spreading in cell cultures is proposed taking into account virus muta...
<p>The evolution of viral diversity, <i>d<sub>G</sub></i>, with generations predicted by our simulat...
Phylogenetic trees can be used to study the evolution of any sequence that evolves, including viruse...
We consider two viral strains competing against each other within individual hosts (at cellular leve...
<p>(a) A linear trade-off between the degree of global infection <i>G</i> (horizontal axis) and that...
<p>The time evolution of the various singly (solid lines) and doubly (dashed lines) infected cell (l...
We describe a stochastic virus evolutionmodel representing genomic diversification and within-host s...