Using an individual-based model, we simulate the behavior of two types of viruses, considering various variables (see README) that influence their generation and multiplication within a selected environment, such as a cell or lesion. The model allows us to manipulate the MOI (between variables a and b) and the bottleneck size (w) to study their effects on viral dynamics
The cellular multiplicity of infection (MOI) is a key parameter for describing the interactions betw...
Many infectious pathogens, and in particular viruses, have an extremely high rate of mutation. This ...
Packaging during the passaging of viruses in cell cultures yields various phenotypes and is regulate...
We consider two viral strains competing against each other within individual hosts (at cellular leve...
We consider two viral strains competing against each other within individual hosts (at cellular leve...
The following thesis explores the within-host population dynamics of viruses and their target cells ...
Viruses play diverse and important roles in ecosystems. In recent years, trade-offs between host and...
Viruses play diverse and important roles in ecosystems. In recent years, trade-offs between host and...
<p>The time-dependent solution of the evolutionary virus dynamics simulation is presented (please no...
A new model of viral infection spreading in cell cultures is proposed taking into account virus muta...
Models of viral population dynamics have contributed enormously to our understanding of the pathogen...
Despite rapidly growing to immense sizes, virus populations suffer repeated severe bottlenecks, both...
<p>A full two-way sensitivity analysis of the model, showing the effect of independently changing pa...
International audienceHigh-throughput sequencing has opened the route for a deep assessment of withi...
Using simulations, we sampled parameters considering both the uncertainty in the estimation and the ...
The cellular multiplicity of infection (MOI) is a key parameter for describing the interactions betw...
Many infectious pathogens, and in particular viruses, have an extremely high rate of mutation. This ...
Packaging during the passaging of viruses in cell cultures yields various phenotypes and is regulate...
We consider two viral strains competing against each other within individual hosts (at cellular leve...
We consider two viral strains competing against each other within individual hosts (at cellular leve...
The following thesis explores the within-host population dynamics of viruses and their target cells ...
Viruses play diverse and important roles in ecosystems. In recent years, trade-offs between host and...
Viruses play diverse and important roles in ecosystems. In recent years, trade-offs between host and...
<p>The time-dependent solution of the evolutionary virus dynamics simulation is presented (please no...
A new model of viral infection spreading in cell cultures is proposed taking into account virus muta...
Models of viral population dynamics have contributed enormously to our understanding of the pathogen...
Despite rapidly growing to immense sizes, virus populations suffer repeated severe bottlenecks, both...
<p>A full two-way sensitivity analysis of the model, showing the effect of independently changing pa...
International audienceHigh-throughput sequencing has opened the route for a deep assessment of withi...
Using simulations, we sampled parameters considering both the uncertainty in the estimation and the ...
The cellular multiplicity of infection (MOI) is a key parameter for describing the interactions betw...
Many infectious pathogens, and in particular viruses, have an extremely high rate of mutation. This ...
Packaging during the passaging of viruses in cell cultures yields various phenotypes and is regulate...