a<p># indicates significantly changed GC species level relative to WT. Data present mean of 3–4 mice per genotype.</p>b<p>c</p><p>nd, not determined.</p
<p>Plate counts of surviving EGDm GAD system mutants 3 days post infection from female Balb/C mice (...
<p>Expression levels of RANK, RANKL and OPG were realtively constant in WT at all time points. Great...
<p>(A) Representative images of BrdU (green) and NeuN (red) staining in the GCL of AC3<sup>+/+</sup>...
<p>Each panel presents GC species levels in mice having the indicated <i>Gba1</i> mutation: D409H (9...
<p>The fold changes of GC species and glucosylsphingosine levels in individual mutant mice were age-...
<p>(A) The mean proportion of each GC species relative to total GC (6 GC species) in age-matched <i>...
<p>All GC species in WT mice showed age-dependent decrease with age (from <1 d, 6–9 wks to 52 wks) i...
<p>Each graph depicts glucosylsphingosine levels in four tissues from mice having the same <i>Gba 1<...
a<p>Summarized from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057560#po...
Gaucher disease results from GBA1 mutations that lead to defective acid β-glucosidase (GCase) mediat...
*<p><i>P</i><0.05;</p>**<p><i>P</i><0.01;</p>***<p><i>P</i><0.001;</p><p>Pooled data from 9–18 month...
<p>(A) Tissue GlcCer species in the lungs, livers, spleens and brains from 9-wk of WT, WT+GCStg, 9V/...
Gaucher disease results from GBA1 mutations that lead to defective acid b-glucosidase (GCase) mediat...
<p>Total GC levels in liver, lung, and spleen from 9V/null (red), 9H/9H (violet), 9V/9V (green), and...
d<p>: vs <i>Gcg<sup>gfp/gfp</sup>Arx<sup>PL/Y</sup></i>, P<0.05. <sup>ee</sup>: vs <i>Gcg<sup>gfp/+<...
<p>Plate counts of surviving EGDm GAD system mutants 3 days post infection from female Balb/C mice (...
<p>Expression levels of RANK, RANKL and OPG were realtively constant in WT at all time points. Great...
<p>(A) Representative images of BrdU (green) and NeuN (red) staining in the GCL of AC3<sup>+/+</sup>...
<p>Each panel presents GC species levels in mice having the indicated <i>Gba1</i> mutation: D409H (9...
<p>The fold changes of GC species and glucosylsphingosine levels in individual mutant mice were age-...
<p>(A) The mean proportion of each GC species relative to total GC (6 GC species) in age-matched <i>...
<p>All GC species in WT mice showed age-dependent decrease with age (from <1 d, 6–9 wks to 52 wks) i...
<p>Each graph depicts glucosylsphingosine levels in four tissues from mice having the same <i>Gba 1<...
a<p>Summarized from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057560#po...
Gaucher disease results from GBA1 mutations that lead to defective acid β-glucosidase (GCase) mediat...
*<p><i>P</i><0.05;</p>**<p><i>P</i><0.01;</p>***<p><i>P</i><0.001;</p><p>Pooled data from 9–18 month...
<p>(A) Tissue GlcCer species in the lungs, livers, spleens and brains from 9-wk of WT, WT+GCStg, 9V/...
Gaucher disease results from GBA1 mutations that lead to defective acid b-glucosidase (GCase) mediat...
<p>Total GC levels in liver, lung, and spleen from 9V/null (red), 9H/9H (violet), 9V/9V (green), and...
d<p>: vs <i>Gcg<sup>gfp/gfp</sup>Arx<sup>PL/Y</sup></i>, P<0.05. <sup>ee</sup>: vs <i>Gcg<sup>gfp/+<...
<p>Plate counts of surviving EGDm GAD system mutants 3 days post infection from female Balb/C mice (...
<p>Expression levels of RANK, RANKL and OPG were realtively constant in WT at all time points. Great...
<p>(A) Representative images of BrdU (green) and NeuN (red) staining in the GCL of AC3<sup>+/+</sup>...
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