NY1682 infection does not prime T cells specific for immunodominant epitopes from PR8’s NP.

<p>B6 mice were infected (bottom) or not (top) with NY1682 i.n. and 25 days later the percentages of D^b/PA_224–38, D^b/NP_366–74 CD8 T cells, or IA^b/NP_311–25 CD4 in the MLN were examined (A). The numbers are the percentages of tetramer+CD44^hi cells out of gated CD8+ or CD4+ live cells that were also dump negative. The serum from these animals was tested for the presence of IgG1 and IgG2c antibody that bound to recombinant PR8 NP with each line representing one mouse (B).