Knockdown of Kindlin 2 inhibits muscle cell differentiation.

<p>(A) The efficacy of Kindlin 2 siRNA was detected by Western blot. (B) Control or Kindlin 2 siRNA was transfected into C2C12 cells. After 24 hr, C2C12 cells were induced myogenic differentiation. At day 3 of differentiation, Western blot analysis was carried out with the indicated antibodies. (C) Protein bands in C were scanned, and relative band intensities were normalized for each β-actin band. The column diagrams represent average relative band intensity with standard error from three independent experiments.