Treatment with streptozotocin reduces prostate tumor growth in PAC120 mouse model.

<p>(<b>A</b>) Pictures of tumors developed in vehicle treated mice (n = 5) (i), STZ treated after or before tumor implantation (n = 7 for both) with reduced (ii) or no tumor growth (iii). (<b>B</b>) Comparison of tumor volume for non-treated (n = 5) and citrate treated (n = 5) mice. (<b>C</b>) Tumor volume of STZ-treated animals after tumor implantation compared with tumor volume of citrate treated mice. (<b>D</b>) Tumor volume of STZ-treated animals before tumor implantation compared with tumor volume of citrate treated mice. Data are mean ± SD. *P<0.05 and **P<0.01 compared with the control.