1d inhibits the growth of tumors derived from HCT116 cells.

<p>HCT116 cells were injected into athymic BALB/c nu/nu mice to induce tumors, and the mice were then treated with <b>1d</b> or DMSO. (A) Representative mice are shown at the end of the treatment. (B) Tumor volume was measured every 3 days after the first injection. (C) Images of representative tumors that were excised at the end of the treatment are shown. (D) The average tumor weights of the control versus the <b>1d</b>-treated group are depicted graphically. (E) Body weight and average diet consumption were recorded. Data are the means ± SEM (n = 6). ***, p<0.001, compared with the control.