<p>A summary chart of all RAS/RAF mutations in each patient group displays genes across in rows and tumors down in columns. The bottom row of each represents the total number of mutations per tumor as a heat map (0-5 mutations). Chart A displays Asian patients, chart B, Black patients and chart C, White patients.</p
<p>Tumor tissue biopsies and biopsy-derived cell lines from 109 metastatic melanoma patients were an...
<p>(A) bar graph shows Ras domains encoded by different genes have different mutation rates across c...
KRAS, NRAS and BRAF are kinases involved in the RAS-RAF-MAPK signaling pathway and also potential tu...
<p>A summary chart of all mutations in each group displays genes across in rows and patient tumors d...
<p>The heatmap shows genes (rows) and tumors (columns) with mutations (blue). The number of events p...
<p>Heat-map representation of individual mutations present in a series of 37 HNSCC tumors, presented...
Mutation frequency within each cancer type ranges from light red (0%) to dark red (≥ 10% of samples)...
<p>Mutation plots showing the amount of genes that need to be sequenced (y-axis) in order to find a ...
<p>Coding mutations in known cancer genes (A) and candidate genes (B) are indicated with different c...
a. The graphical summary of somatic mutations of the 4 genes in molecular subtypes. All of the 190 t...
<p>A) Heatmap of number of variants per tumour group. On the y-axis the different primary tumour sit...
<p>A) Chromatogram showing relative intensities of each base pair after Sanger sequencing in both th...
A) Number of mutations (left panel) and number of clones (right panel) in tumor types and subtypes w...
Cartoon diagrams of RAD52, BRCA2, BRCA1 and PALB2 showing specific domains in each gene. The diagram...
<p>Scheme showing an approximated representation of the location of each lesion analysed in patient-...
<p>Tumor tissue biopsies and biopsy-derived cell lines from 109 metastatic melanoma patients were an...
<p>(A) bar graph shows Ras domains encoded by different genes have different mutation rates across c...
KRAS, NRAS and BRAF are kinases involved in the RAS-RAF-MAPK signaling pathway and also potential tu...
<p>A summary chart of all mutations in each group displays genes across in rows and patient tumors d...
<p>The heatmap shows genes (rows) and tumors (columns) with mutations (blue). The number of events p...
<p>Heat-map representation of individual mutations present in a series of 37 HNSCC tumors, presented...
Mutation frequency within each cancer type ranges from light red (0%) to dark red (≥ 10% of samples)...
<p>Mutation plots showing the amount of genes that need to be sequenced (y-axis) in order to find a ...
<p>Coding mutations in known cancer genes (A) and candidate genes (B) are indicated with different c...
a. The graphical summary of somatic mutations of the 4 genes in molecular subtypes. All of the 190 t...
<p>A) Heatmap of number of variants per tumour group. On the y-axis the different primary tumour sit...
<p>A) Chromatogram showing relative intensities of each base pair after Sanger sequencing in both th...
A) Number of mutations (left panel) and number of clones (right panel) in tumor types and subtypes w...
Cartoon diagrams of RAD52, BRCA2, BRCA1 and PALB2 showing specific domains in each gene. The diagram...
<p>Scheme showing an approximated representation of the location of each lesion analysed in patient-...
<p>Tumor tissue biopsies and biopsy-derived cell lines from 109 metastatic melanoma patients were an...
<p>(A) bar graph shows Ras domains encoded by different genes have different mutation rates across c...
KRAS, NRAS and BRAF are kinases involved in the RAS-RAF-MAPK signaling pathway and also potential tu...