Enhanced resistance of p110δ^D910A mice is not associated with more robust granuloma formation.

<p>Infected p110δ^D910A and WT mice were sacrificed at the indicated times and their liver were processed and stained routinely to assess granuloma formation (size, cellularity and maturation) as described in the materials and methods section. The H&E stained sections (A) were assessed and scored blindly by a pathologist for the presence/number of ineffective, developing and mature granulomas and represented as a bar graph (B). Results are representative of 2 independent experiments (n = 3 mice per group) with similar results. Error bars, +/− SEM; *, p < 0.05; **, p < 0.01; ***, p < 0.001.