<p>(A) Graph showing the granuloma area in liver of vaccinated mice. Representative granulomas of (B) pUMVC3; (C) pUMVC3/Sm29; (D) pUMVC3/TSP-2; (E) pUMVC3/Chimera; (F) pUMVC3/Sm29 + pUMVC3/TSP-2 are demonstrated. The scale bar corresponds to 50 μm. Significant differences from mice immunized with the pUMVC3 control are denoted by an asterisk (*) for p<0.05, and the percent reductions are shown.</p
<p>(A) granuloma sizes calculated from isolated granulomas at 43 days after infection calculated fro...
<p>Groups of mice were vaccinated with BCG-Gag, BCG-Control, BCGpan-Gag or BCGpan-Control (10<sup>7<...
<p>(A) Representative liver sections taken from the control mice, 29.5 mg/kg, 103.5 mg/kg and 177.5 ...
<p>The r<i>Sm</i>10.3-vaccinated and control animals from the first vaccination trial were sacrifice...
<p>Representative granulomas from acutely infected, DT treated CCR2-DTR (<b>A</b>–<b>F</b>) and WT m...
*<p> <b>Statistically significant compared with the control group (p<0.05).</b></p
<p>Representative picture of granuloma reaction (A) and the measurement of granuloma area of each gr...
<p>Groups of mice were infected with 30–35 Sm cercariae. Some groups were treated twice with PZQ aft...
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>Worm burden (mean +/− SD) in control mice injected with PBS versus mice immunized with r<i>Sm</i>...
<p>Quantification of granuloma formation in the liver of <i>L. donovani</i> infected WT and Jα18<sup...
<p>(A) Representative slides of small (Day 15) and large (Day 60) hepatic granulomas labeled by immu...
<p>Infected p110δ<sup>D910A</sup> and WT mice were sacrificed at the indicated times and their liver...
<p>Infected p110δ<sup>D910A</sup> and WT mice were sacrificed at the indicated times and their liver...
<p><b>(A)</b> Representative images of hematoxylin/eosin (HE) and Sirius Red (SR)-stained liver slic...
<p>(A) granuloma sizes calculated from isolated granulomas at 43 days after infection calculated fro...
<p>Groups of mice were vaccinated with BCG-Gag, BCG-Control, BCGpan-Gag or BCGpan-Control (10<sup>7<...
<p>(A) Representative liver sections taken from the control mice, 29.5 mg/kg, 103.5 mg/kg and 177.5 ...
<p>The r<i>Sm</i>10.3-vaccinated and control animals from the first vaccination trial were sacrifice...
<p>Representative granulomas from acutely infected, DT treated CCR2-DTR (<b>A</b>–<b>F</b>) and WT m...
*<p> <b>Statistically significant compared with the control group (p<0.05).</b></p
<p>Representative picture of granuloma reaction (A) and the measurement of granuloma area of each gr...
<p>Groups of mice were infected with 30–35 Sm cercariae. Some groups were treated twice with PZQ aft...
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>Worm burden (mean +/− SD) in control mice injected with PBS versus mice immunized with r<i>Sm</i>...
<p>Quantification of granuloma formation in the liver of <i>L. donovani</i> infected WT and Jα18<sup...
<p>(A) Representative slides of small (Day 15) and large (Day 60) hepatic granulomas labeled by immu...
<p>Infected p110δ<sup>D910A</sup> and WT mice were sacrificed at the indicated times and their liver...
<p>Infected p110δ<sup>D910A</sup> and WT mice were sacrificed at the indicated times and their liver...
<p><b>(A)</b> Representative images of hematoxylin/eosin (HE) and Sirius Red (SR)-stained liver slic...
<p>(A) granuloma sizes calculated from isolated granulomas at 43 days after infection calculated fro...
<p>Groups of mice were vaccinated with BCG-Gag, BCG-Control, BCGpan-Gag or BCGpan-Control (10<sup>7<...
<p>(A) Representative liver sections taken from the control mice, 29.5 mg/kg, 103.5 mg/kg and 177.5 ...