<p>Representative picture of granuloma reaction (A) and the measurement of granuloma area of each group (B). To determine granuloma area, approximately 100 granulomas from IT/rSm29 group and from its control group (IT/Saline), with a single well-defined egg (exudative stage), were measured. Total area of the granulomas was expressed in square micrometers (μm<sup>2</sup>). Scale bar = 100 μm (x100).</p
<p>Localization by immunohistofluorescence of (<b>A</b>) F4/80, (<b>B</b>) CD11b, (<b>C</b>) CD11c a...
<p>(A) Columns indicate volumetric proportions of tissue components. The number of portal space, cen...
<p>Antigen (GST or GST-SjE16.7) coupled or uncoupled beads (Control) were injected into C57BL6/J mou...
<p>The r<i>Sm</i>10.3-vaccinated and control animals from the first vaccination trial were sacrifice...
<p>(A) Graph showing the granuloma area in liver of vaccinated mice. Representative granulomas of (B...
<p>Quantification of granuloma formation in the liver of <i>L. donovani</i> infected WT and Jα18<sup...
<p>A and B: Liver of treated infected animals (40 mg/kg). Note the necrotic-exudative phase with loo...
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>Representative granulomas from acutely infected, DT treated CCR2-DTR (<b>A</b>–<b>F</b>) and WT m...
<p>(A) granuloma sizes calculated from isolated granulomas at 43 days after infection calculated fro...
<p>(A) Representative slides of small (Day 15) and large (Day 60) hepatic granulomas labeled by immu...
<p>Infected p110δ<sup>D910A</sup> and WT mice were sacrificed at the indicated times and their liver...
<p>(A) Representative liver sections taken from the control mice, 29.5 mg/kg, 103.5 mg/kg and 177.5 ...
<p>Infected p110δ<sup>D910A</sup> and WT mice were sacrificed at the indicated times and their liver...
<p>Difference was significant ** <i>P</i><0.01.</p><p>Granuloma diameter (μm) in the liver of the mi...
<p>Localization by immunohistofluorescence of (<b>A</b>) F4/80, (<b>B</b>) CD11b, (<b>C</b>) CD11c a...
<p>(A) Columns indicate volumetric proportions of tissue components. The number of portal space, cen...
<p>Antigen (GST or GST-SjE16.7) coupled or uncoupled beads (Control) were injected into C57BL6/J mou...
<p>The r<i>Sm</i>10.3-vaccinated and control animals from the first vaccination trial were sacrifice...
<p>(A) Graph showing the granuloma area in liver of vaccinated mice. Representative granulomas of (B...
<p>Quantification of granuloma formation in the liver of <i>L. donovani</i> infected WT and Jα18<sup...
<p>A and B: Liver of treated infected animals (40 mg/kg). Note the necrotic-exudative phase with loo...
<p>(A) Representative hepatic granulomas of 8-week-infected drug-untreated and drug-treated mice. Ph...
<p>Representative granulomas from acutely infected, DT treated CCR2-DTR (<b>A</b>–<b>F</b>) and WT m...
<p>(A) granuloma sizes calculated from isolated granulomas at 43 days after infection calculated fro...
<p>(A) Representative slides of small (Day 15) and large (Day 60) hepatic granulomas labeled by immu...
<p>Infected p110δ<sup>D910A</sup> and WT mice were sacrificed at the indicated times and their liver...
<p>(A) Representative liver sections taken from the control mice, 29.5 mg/kg, 103.5 mg/kg and 177.5 ...
<p>Infected p110δ<sup>D910A</sup> and WT mice were sacrificed at the indicated times and their liver...
<p>Difference was significant ** <i>P</i><0.01.</p><p>Granuloma diameter (μm) in the liver of the mi...
<p>Localization by immunohistofluorescence of (<b>A</b>) F4/80, (<b>B</b>) CD11b, (<b>C</b>) CD11c a...
<p>(A) Columns indicate volumetric proportions of tissue components. The number of portal space, cen...
<p>Antigen (GST or GST-SjE16.7) coupled or uncoupled beads (Control) were injected into C57BL6/J mou...