Clustering analysis showing differential methylation in episomal iPS cells compared with virally induced iPS cells.

<p>(A) The heat map of hierarchical clustering analysis represents DNA methylation levels from completely methylated (red) to unmethylated (green). (B) 0.14% of CpG sites are differential in episomally derived AF-IPS cells compared with virally derived AF-IPS cells. It should be noted that 591 of the DMRs are hypomethylated.