Susceptibility to obesity-induced insulin resistance is not altered in klrk^-/- mice.

<p>(A) Body weight of WT and klrk^-/- mice placed on normal diet or high-fat diet for 18 weeks. (B) Fasting blood glucose levels measured after 0, 6, 12, and 18 weeks on high-fat diet. (C) Glucose tolerance test and (D) insulin tolerance test performed after 0, 6, 12, and 18 weeks on high-fat diet. The numbers of mice used for each experiments were at least 10 for WT normal diet, at least 9 for WT high-fat diet, at least 16 for klrk^-/- normal diet, and at least 18 for klrk^-/- high-fat diet.