Chronic hypoxia increased TRPC6 expression in PV from hypoxia exposed rats.

<p>TRPC expression in distal PV tissue from rats exposed to normoxia or hypoxia (10% O₂, 21 days). <b>A</b> and <b>B</b>: the mRNA expression of TRPC1 and TRPC6 in distal PV from rats exposed to hypoxia (10% O₂) for different days compared with that in control group. <b>C</b> and <b>D</b>: TRPC1 and TRPC6 proteins expression determined by Western blotting. Representative blots (C) and mean intensity (D) for TRPC1 and TRPC6 blots relative to a-actin. Bar values are mean±SEM (n = 3 in each group). *P<0.05 versus respective normoxia control.