Prolonged hypoxia up-regulated transient receptor potential 6 (TRPC6) expression <i>in vitro</i>.

<p><b>A</b>: TRPC1 and TRPC6 mRNA relative to 18s determined by real-time quantitative PCR. <b>B</b> and <b>C</b>: TRPC1 proteins determined by Western blotting. Representative blots (B) and mean intensity (C) for TRPC1 blots relative to α-actin. <b>D</b> and <b>E</b>: TRPC6 proteins determined by Western blotting. Representative blots (D) and mean intensity (E) for TRPC1 blots relative to α-actin. Bar values are mean ± SEM (n = 3 in each group). *P<0.05 versus respective normoxia control.