<p>TLR2, IFN-γ and TNF-α gene expression in NK cells of healthy controls (n = 5), LCL (n = 6) and DCL (n = 3) patients.</p><p><b>1</b>. C_S vs C_NS; <b>2</b>. LCL_S vs LCL_NS; <b>3</b>. DCL_S vs DCL_NS; <b>4</b>. LCL_NS vs C_NS; <b>5</b>. DCL_NS vs C_NS; <b>6</b>. DCL_NS vs LCL_NS; <b>7</b>. LCL_S vs C_S; <b>8</b>. DCL_S vs C_S; <b>9</b>. DCL_S vs LCL_S. C: healthy controls, LCL: patients with localized cutaneous leishmaniasis, DCL: patients with diffuse cutaneous leishmaniasis. *p<0.05 significant differences.</p><p>Transcript expression by quantitative real time PCR in non-stimulated (NS) and LPG-stimulated NK cells (S).</p
Relatively little is known about development of the Natural Killer (NK) cell. Studies in the past h...
<p>(A) TNF-α production in peripheral blood [control subjects (n = 21), LCL patients (n = 28) and D...
<p>(A) IFN-γ production of peripheral blood NK cells [control subjects (n = 21), LCL patients (n = ...
<div><p>An important NK-cell inhibition with reduced TNF-α, IFN-γ and TLR2 expression had previously...
Leishmania mexicana causes localized (LCL) or diffuse cutaneous leishmaniasis (DCL). The cause of di...
<p>(A) Representative flow cytometry dot plot (TLR2 vs. CD56) and histogram of TLR2 expression in NK...
<p>(A) Representative flow CD56<sup>+</sup>/CD3<sup>-</sup> expression in membranes of NK cells; rig...
<p>(A) The expression of the indicated genes was tested by qPCR in PBMCs, K562 cells and three hiPSC...
<p><strong><em>Background:</em></strong> Natural killer (NK) cells play an important role in early s...
<p>(A) KIR expression during ex vivo expansion. All NK cultures were independently stained for the i...
<p>(A and B) Western blot shows TLR1 and TLR6 in NK cells. (C and D) Immunoprecipitations were perfo...
<p>PBLs from the controls (N, <i>n</i> = 19) or patients with CRS (<i>n</i> = 18) were incubated wit...
<p>The frequencies of KIR3DL05<sup>+</sup> (A), KIR3DL01<sup>+</sup> (B) and KIR3DL01<sup>-</sup>05<...
<p>(A) Western blot of mature IL-1β (17 kDa) in 4 controls (1–4), 9 LCL patients (5–13) and 7 DCL pa...
SummaryNatural killer (NK) cells play a well-recognized role in early pathogen containment and in sh...
Relatively little is known about development of the Natural Killer (NK) cell. Studies in the past h...
<p>(A) TNF-α production in peripheral blood [control subjects (n = 21), LCL patients (n = 28) and D...
<p>(A) IFN-γ production of peripheral blood NK cells [control subjects (n = 21), LCL patients (n = ...
<div><p>An important NK-cell inhibition with reduced TNF-α, IFN-γ and TLR2 expression had previously...
Leishmania mexicana causes localized (LCL) or diffuse cutaneous leishmaniasis (DCL). The cause of di...
<p>(A) Representative flow cytometry dot plot (TLR2 vs. CD56) and histogram of TLR2 expression in NK...
<p>(A) Representative flow CD56<sup>+</sup>/CD3<sup>-</sup> expression in membranes of NK cells; rig...
<p>(A) The expression of the indicated genes was tested by qPCR in PBMCs, K562 cells and three hiPSC...
<p><strong><em>Background:</em></strong> Natural killer (NK) cells play an important role in early s...
<p>(A) KIR expression during ex vivo expansion. All NK cultures were independently stained for the i...
<p>(A and B) Western blot shows TLR1 and TLR6 in NK cells. (C and D) Immunoprecipitations were perfo...
<p>PBLs from the controls (N, <i>n</i> = 19) or patients with CRS (<i>n</i> = 18) were incubated wit...
<p>The frequencies of KIR3DL05<sup>+</sup> (A), KIR3DL01<sup>+</sup> (B) and KIR3DL01<sup>-</sup>05<...
<p>(A) Western blot of mature IL-1β (17 kDa) in 4 controls (1–4), 9 LCL patients (5–13) and 7 DCL pa...
SummaryNatural killer (NK) cells play a well-recognized role in early pathogen containment and in sh...
Relatively little is known about development of the Natural Killer (NK) cell. Studies in the past h...
<p>(A) TNF-α production in peripheral blood [control subjects (n = 21), LCL patients (n = 28) and D...
<p>(A) IFN-γ production of peripheral blood NK cells [control subjects (n = 21), LCL patients (n = ...